primary hyperparathyroidism


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Related to primary hyperparathyroidism: Secondary hyperparathyroidism

pri·mar·y hy·per·par·a·thy·roid·ism

hyperparathyroidism due to neoplasms or idiopathic hyperplasia of the parathyroid glands.

primary hyperparathyroidism

Parathyroid related hypercalcemia Endocrinology Parathyroid gland hyperactivity with excess PTH secretion because of hyperplasia or adenoma of 1 or more glands Clinical Calcium deposits may occur in bone, the GI tract, kidney, muscle, and CNS; it most commonly affects those between 30 and 50 yrs, and is more common in women. See Familial adenoma.

primary hyperparathyroidism

Hyperparathyroidism caused by a parathyroid adenoma. Its laboratory hallmark is a high (or normal) parathyroid hormone level despite elevated concentrations of calcium in the serum.
References in periodicals archive ?
The diagnosis of primary hyperparathyroidism was based on the presence of hypercalcemia and an elevated intact PTH level before surgical consultation.
Generally, surgery is the mainstay of treatment of primary hyperparathyroidism, particularly for the patient younger than 50 years, the symptomatic patient, and those who cannot be closely monitored medically.
Primary hyperparathyroidism is characterized by both increased levels of PTH and calcium and both of these have been shown to stimulate adrenocortical steroid production in various in vitro and in vivo studies (2-8).
In the case described above, primary hyperparathyroidism was suspected because of his PTH being within the normal range in presence of hypercalcemia as any elevation in serum calcium should suppress the PTH unless the parathyroid glands are autonomous or non-responsive.
However, considering that a solitary parathyroid adenoma is the culprit in 85% of patients with primary hyperparathyroidism, a bilateral neck exploration to identify all parathyroid glands is often unnecessary.
The study included only cases of primary hyperparathyroidism diagnosed between the return of the 1986 questionnaire and May 31, 2008.
Transient hypocalcemia occurs after surgery for primary hyperparathyroidism in 15% to 30% of patients (6-8).
If you see primary hyperparathyroidism in mothers with vitamin D-deficiency osteomalacia: Think of Tertiary.
Our objective was to determine whether N-PTH is overproduced in parathyroid cancer, the severest form of primary hyperparathyroidism (PHPT) and, if so, whether this overproduction is affected by therapy with the calcimimetic cinacalcet.
A There is a direct correlation between parathyroid hormone concentrations and calcium in primary hyperparathyroidism, which is not seen in secondary hyperparathyroidism due to renal failure.
Primary hyperparathyroidism is characterized by hypersecretion of parathyroid hormone in spite of hypercalcemia.

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