hyperoxaluria /hy·per·ox·al·uria/ (-ok″sah-lu″re-ah) an excess of oxalates in the urine.
hyperoxaluria (hī´p
rok´sl
r´ē),
primary hyperoxaluria
enteric hyperoxaluria formation of calcium oxalate calculi in the urinary tract after resection or disease of the ileum, due to excessive absorption of oxalate from the colon.
primary hyperoxaluria an inborn error of metabolism with defective glyoxylate metabolism, excessive urinary excretion of oxalate, nephrolithiasis, nephrocalcinosis, early onset of renal failure, and often a generalized deposit of calcium oxalate.
hyperoxaluria (hī´p
rok´slr´ē),n an excessive level of oxalic acid or oxalates, primarily calcium oxalate, in the urine. The cause is usually an inherited deficiency of an enzyme needed to metabolize oxalic acid, which is present in many fruits and vegetables, or a disorder of fat absorption in the small intestine. An excess of oxalates may lead to the formation of renal calculi. Treatment may include pyridoxine, forced fluid, and a low-oxalate diet.
hyperoxaluria, primary,
n an inherited deficiency of the enzyme that metabolizes oxalic acid, resulting in an excessive level of oxalic acid or oxalates in the urine.
hyperoxaluria
an excess of oxalate in the urine; occurs in dogs in association with oxalate urolith formation.
primary hyperoxaluria
inherited metabolic defect in cats. Characterized by heavy deposits of oxalates in renal tubules, leading to oxalate nephrosis and fatal uremia before the patient reaches a year of age.
primary hyperoxaluria
Oxalosis An AR condition characterized by crystallization in tissues Clinical Calcium oxalate–CO is ↑↑↑ in urine, resulting in CO supersaturation crystalluria, stone formation, and deposition of CO
in the renal parenchyma, leading to renal dysfunction and CO deposition in multiple organs–oxalosis Treatment Orthophosphate, pyridoxine Prognosis With therapy, actuarial ESRD-free survival at 20 yrs is ± 75%; sans therapy, 80% have
ESRD by the 3rd decade of life; renal transplants do not survive well; liver transplants may be used to correct the enzyme defect
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