primaquine


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primaquine

 [pri´mah-kwin]
an antimalarial agent effective against the extraerythrocytic forms of Plasmodium vivax and P. ovale and the gametocytes of P. falciparum, used especially in the treatment of relapsing vivax malaria; used orally as the phosphate salt.

primaquine

/prim·a·quine/ (prim´ah-kwēn) an 8-aminoquinoline compound used as an antimalarial in the form of the phosphate salt.

primaquine

(prē′mə-kwēn′, -kwĭn, prī′-)
n.
A drug, C15H21N3O, used in its phosphate form as an antimalarial, especially to prevent relapses.

primaquine

A drug used in the treatment of Plasmodium vivax and Plasmodium ovale MALARIA. The drug is on the WHO official list.

primaquine

an antiprotozoal agent used as the phosphate in the treatment of theileriosis, babesiosis, leishmaniasis and trypanosomiasis.
References in periodicals archive ?
The use of primaquine in malaria infected patients with red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency in Myanmar.
The study, carried out in Jinja, Uganda, treated G6PD-normal children with a conventional anti-malarial drug either on its own or with one of three different doses of primaquine.
Two of the drugs she was prescribed, quinine and primaquine, are associated with haemolysis in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
A new 8-aminoquinoline tafenoquine is on clinical trial as a potential replacement for primaquine to treat Plasmodium vivax malaria (Shanks 2001) and holds promise as a prophylactic against Plasmodium falciparum (Shanks 2001).
4) Inherited deficiency of glucose-6-phosphate dehydrogenase (G6PD) was shown to cause severe hemolysis seen in some patients exposed to the antimalarial drug primaquine.
vivax, a two-week course of primaquine for hypnozoite clearance was administered.
It was observed during World War II that drug-induced hemolysis was much more prevalent among African-American soldiers than Caucasian-American soldiers who had been given the anti-malarial drug primaquine.
Clinical and laboratorial alterations in Plasmodium vivax malaria patients and glucose-6-phosphate dehydrogenase deficiency treated with primaquine at 0.
Because of its action in the hypnozoites, a two-week course of primaquine after return from travel is effective in preventing the late-onset malaria.
The goal of the study is to detemtine the mechanism of action of primaquine against P.
md 491 29 Pervyye Vybory v Verkhovnyy Sovet, Russia, 56[degrees]53, 121[degrees]04 492 34 Otdeleniye Nomer 1 Sovkhoza Suvorovskiy, Kazakhstan, 53[degrees]17, 74[degrees]35 34 tryin' to scratch your ear with your elbow, Anne Bertram: In a Pig's Eye, The Dictionary of Country Jawing 493 32 Ostanovochnyy Punkt Pyatyy Kilometr, Russia, 44[degrees]10, 43[degrees]08 37 8-(4-amino-1-methylbutylamino)-6-methoxyquinoline, OED primaquine 494 32 Stantsiya Armavir Pervyy Rostovskiy, Russia, 44[degrees]59, 41[degrees]07 495 34 Kung-shan-tu-lung-tsu-nu-tsu-tzu-chih-hsien, China, 27[degrees]41, 98[degrees]37 37 honest-to-goodness-twelve-months-in-the-year, OED honest 4d, 1916q 40 aminoheptafluorocyclotetraphosphonitrile, www.