prilocaine hydrochloride


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prilocaine hydrochloride

[pril′ōkān]
a local anesthetic agent of the amide family, used for nerve block, epidural, and regional anesthesia. It is not used for spinal or topical anesthesia. Prilocaine hydrochloride is about half as toxic as lidocaine but, because methemoglobinemia is a possible reaction to its administration, is not used for patients with hypoxic conditions of any kind.

prilocaine hydrochloride (local),

n brand name: Citanest, Citanest Forte;
drug class: amide local anesthetic;
action: inhibits ion fluxes across membranes, particularly sodium transport across cell membrane; decreases rise of depolarization phase of action potential; blocks nerve action potential;
use: local dental anesthesia.
References in periodicals archive ?
The electric current made the prilocaine hydrochloride enter the body more effectively; the permeation of the anesthetic through the mouth lining increased 12-fold.