On the other hand, increased activin-A concentrations have been observed in the amniotic fluid of patients who subsequently died of intrauterine fetal hypoxia (20) and in the plasma of hypoxic preterm newborns (12).
We found that activin A showed 100% sensitivity and 88% specificity as a single marker for the prediction of hypoxic-ischemic brain insult in preterm newborns.
In conclusion, activin A concentrations are increased in preterm newborns who develop IVH.
Full-term newborns and preterm newborns both are significantly more likely to be admitted to L2/3 care at Site A than are newborns of similar maturity in the other three sites (p [less than].
Among preterm newborns, sites differ significantly only on SNAP (Table 3).
Among preterm newborns, for example, the likelihood of admission into L2/3 care versus L1 care decreases significantly with increases in gestational age--standardized birth weight, gestational age, or unit increases in five-minute Apgar scores; however, it increases significantly with unit increases in VSSNAP (Table 4).
When any duration of L2/3 stay is considered to be an L2/3 admission, both preterm newborns and full-term newborns at Site B and Site C are significantly less likely to be admitted to L2/3 care than are newborns in Site A (Table 4).
When an L2/3 stay of 24 hours or longer is considered to be an L2/3 admission, both preterm newborns at Sites B and C and full-term newborns at the two sites are less likely to be admitted to L2/3 care than are newborns in Site A (Table 4).
3] Among preterm newborns, for example, duration of stay in L3 care is significantly shortened with unit increases in gestational age-standardized birth weight or unit increases in gestational age; however, it is significantly prolonged with unit increases in SNAP.
We performed a case-control study on 18 preterm newborns (29-35 weeks of gestation) with IVH in whom urine S100B was measured at first urination (time 0) and at 24 (time 1), 48 (time 2), and 72 h of age (time 3).
In addition, because renal function also appears to be normal in preterm infants, the different S100B urine concentrations observed in preterm newborns cannot reasonably be ascribed to different degrees of urine concentration.