plasticity in an immature neocortical network requires NMDA receptor activation and BDNF release.
Once released, the endocannabinoid ligands diffuse, acting locally as retrograde messengers to regulate the release of multiple presynaptic
First, connectivity of the neurons in CNS is complex, and reliable identification of presynaptic
neurons connecting to their target is sometimes impossible because of the lack of appropriate markers.
The thing is, dopamine is a very reactive molecule when it isn't packaged by VMAT-2, and when it autooxidizes in the presynaptic
cytosol, it can actually damage the presynaptic
Neonatal propofol exposure regulates miniature inhibitory postsynaptic currents via an action potential-dependent and/or potential-independent presynaptic
fade] and Fade caused by this agent, since the mechanisms that regulate acetylcholine release via presynaptic
muscarinic and adenosine receptors are differently affected by TOF and tetanic stimulations conditions (Bornia et al.
The frequency of mEPSCs represents the release quantity of glutamate from the presynaptic
membrane, and the amplitude represents the amount of opened postsynaptic glutamatergic receptors.
This model makes use of neuron activity decay of nodes to achieve short-term memory, connection weights between different nodes to represent long-term memory, presynaptic
potentials and neuron synchronized activation mechanism to realize identifying and recalling, and a time-delayed Hebb learning mechanism to fulfil the one-shot learning.
induced glutamate release in the hippocampus, probably via presynaptic
suppression of intracellular [Ca.
Radiolabeled dopa (carbon-11 or fluorine-18) is transported into presynaptic
dopaminergic neurons in the striatum, where it is decarboxylated, converted to radio-dopamine, and stored within vesicles until released in response to neuronal excitation.
Conclusion: These results indicate that TEN enhances the basic synaptic transmission via stimulating presynaptic
Strength and precision of neurotransmission at mammalian presynaptic
terminals Tomoyuki TAKAHASHI Mechanism of the calcium-regulation of muscle contraction--In pursuit of its structural basis--Takeyuki WAKABAYASHI Above two, communicated by Masanori OTSUKA, M.