presynaptic


Also found in: Dictionary, Wikipedia.
Related to presynaptic: presynaptic membrane

presynaptic

 [pre″sĭ-nap´tik]
situated or occurring proximal to a synapse.

pre·syn·ap·tic

(prē'sin-ap'tik),
Pertaining to the area on the proximal side of a synaptic cleft.

presynaptic

/pre·syn·ap·tic/ (-sĭ-nap´tik) situated or occurring proximal to a synapse.

presynaptic

(prē′sĭ-năp′tĭk)
adj.
Situated in front of or occurring before a synapse: a presynaptic nerve fiber; a presynaptic stimulus.

presynaptic

[-sinap′tik]
Etymology: L, prae + synaptein, to join
1 situated near or before a synapse.
2 before a synapse is crossed.

pre·syn·ap·tic

(prē'si-nap'tik)
Pertaining to the area on the proximal side of a synaptic cleft.

presynaptic

proximal side of a synapse

presynaptic

situated or occurring proximal to a synapse.
References in periodicals archive ?
Increased presynaptic dopamine restores some of the effects of substantia nigra cell loss, leading to increased smooth and coordinated movement through the direct and indirect pathways in the dopamine neurotransmitter system.
When an action potential arrives at the presynaptic axonal terminal, depolarization opens voltage-gated [Ca.
In another experiment using a genetic model of Fragile X, the flies had presynaptic terminals almost a third longer than normal, but those that received the drug saw only 3 percent more terminal growth than the control group.
For this change to occur, the presynaptic and postsynaptic neurons must be activated during the release of dopamine.
Buspirone is a nonbenzodiazepine medication that appears to produce antianxiety effects through both presynaptic and postsynaptic serotonin-1A receptors.
1:30 "Halothane enhances presynaptic GABA release by increasing intracellular calcium from ryanodine-sensitive stores.
By enhancing presynaptic inhibition, benzodiazpines suppress the spread of seizure activity.
Their spatio-temporal organization in the post synapse with respect to presynaptic glutamate release sites is a key determinant in synaptic transmission.
For LY2140023, the active substance, LY404039, is thought to work by reducing the presynaptic release of another neurotransmitter, glutamate, in brain regions where mGlu2/3 receptors are expressed.
P/Q-type VGCCs, which are distributed widely throughout the brain and are present at motor nerve terminals in the neuromuscular junction, play an integral role in presynaptic neurotransmitter release at nerve terminals (6).
Citalopram normally targets the presynaptic serotonin transporter but also binds to the serotonin 2A receptor, which is located postsynaptically.