presenilin gene


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presenilin gene

Rare traits responsible for early-onset Alzheimer's disease.
See also: gene
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42], in a manner similar to presenilin gene mutations that cause familial AD.
Nixon, indicate that similar disruptions of the cellular protein-recycling process occur in neurons affected by late-onset Alzheimer's, suggesting that factors other than mutations in the presenilin gene can also impair this process.
Researchers from the Mailman Research Center, McLean Hospital, Belmont, Massachusetts, found that presenilin gene mutations induce more severe damage to lysosomal systems in the brains of people dying with FAD than that seen in brains of individuals with the more common late-onset AD (Cataldo et al.