Higher levels of those, still at a prepsychotic
level, but at a higher, prodromal level of activity, predicts psychosis with pretty high accuracy on their own," he said.
The diagnoses suspected by the psychiatrists were "reactive depression, prepsychotic
personality, obsessive-compulsive disorder, narcissistic personality disorder" and he was started on many antidepressants and antipsychotics.
This constellation of existential guilt, risk-taking behaviors, sense of impending doom and prepsychotic
terror appears to be distinct from symptoms that may arise in other types of pregnancy-loss survival situations, from childhood mistreatment, or from an abortion experienced by the individual or the individual's partner.
Treatment with antidepressants kept adolescent patients in the prepsychotic
phase of schizophrenia from progressing to full psychosis or bipolar disorder more effectively than did treatment with antipsychotics, said Barbara A.
Recent studies have shown independent therapeutic effects of antipsychotic medication and cognitive-behavioral therapy during the interval between the first noticeable prepsychotic
changes and the onset of positive psychotic symptoms--findings that should compel investigators to ramp up research efforts to identify optimal prodromal management strategies, he said.