08% (n = 18/78) of offspring presented with neoplastic lesions (HCCs or hepatic adenomas) or preneoplastic
lesions (hyperplastic nodules), with an odds ratio (OR) of 7.
In vivo, CBD BDS reduced AOM-induced preneoplastic
lesions and polyps as well as tumour growth in the xenograft model of colon cancer.
Dose response and proliferative characteristics of aberrant crypt foci: putative preneoplastic
lesions in the rat colon.
lesion growth driven by the death of adjacent normal stem cells.
They address epidemiology, the histopathology of various tumors, current imaging techniques, molecular pathology, staging, preneoplastic
and preinvasive lesions, pitfalls, differential diagnosis, and complications, with many images.
These included rat studies showing some associations with lower levels of BPA exposure regarding "sex-specific neurodevelopment, anxiety, preneoplastic
changes in mammary glands and prostate in rats, [and] impaired sperm parameters).
There is a limited discussion of preventive and therapeutic vaccines, which are FDA-approved in preneoplastic
conditions such as human papillomavirus (HPV).
Increase in hepatocyte and nuclear volume and decrease in the population of binucleated cells in preneoplastic
foci of rat liver: a stereological study using the nucleator method.
Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic
and neoplastic lesions.
Retinoid compounds have also shown promise in treating preneoplastic
and cancerous lesions.
Topics addressed include: cancer therapy by angiogenesis inhibition, the role of angiogenesis in the development of preneoplastic
lesions in hepatocellular carcinoma, vaccines targeting tumor angiogenesis, the role of endothelial progenitor cells in tumor angiogenesis, and metastasis suppression by SSeCKS/Gravin/AKA-P12 through the inhibition of angiogenesis.
Alpha (2)- macroglobulin: a novel cytochemical marker characterizing Preneoplastic
and neoplastic rat liver lesions negative for hitherto Established cytochemical markers.