prenatal test

prenatal test

Obstetrics Any lab test or assay used to detect genetic and/or congenital fetal anomalies that would compromise the infant's well-being and quality of life to such a degree that the parents might prefer an abortion Examples α-fetoprotein levels in mother's serum or amniotic fluid, chromosome analysis, ultrasonography, chorionic villus biopsy–8th-10th gestational wks, risk of spontaneous abortion/miscarriage–1.0-1.5%, amniocentesis–16th gestational wk, risk of spontaneous abortion/miscarriage– 0.5%, fetoscopy, embryoscopy Diseases detected α1-antitrypsin activity, thalassemias, defects of sex and autosomal chromosomes, eg, trisomies, deletions, mosaicisms, fragile X syndrome, hemophilia, neural tube defects–anencephaly, spina bifida, polycystic kidney disease, Tay-Sachs disease. See Embroscopy, Fetoscopy. Cf Wrongful birth.
References in periodicals archive ?
MaterniT21 PLUS was the first non-invasive prenatal test introduced in the market in 2011 for the diagnosis of trisomy 21.
today announced a strategic agreement for expanding access to Verinata's verifi([R])test, the most comprehensive non-invasive prenatal test (NIPT) currently available for high-risk pregnancies.
Ariosa s proprietary HarmonyTM Prenatal Test is a blood test that is performed as early as 10 weeks into pregnancy.
3] Moreover, negative (or reassuring) prenatal test results will reduce the anxiety felt by many prospective parents, and this in itself can be construed as part of good prenatal care.
Upon completion of the acquisition, Illumina will have access to Verinata's verifi[R] prenatal test, the broadest non-invasive prenatal test (NIPT) available today for high-risk pregnancies, and to the most comprehensive intellectual property portfolio in the non-invasive prenatal test industry.
1] technology and maker of the Harmony(TM) Prenatal Test, today announced the results of a new clinical study on the company's targeted cell-free DNA analysis using microarray quantitation which demonstrated high sensitivity, specificity and extremely low false positive rates for prenatal assessment of Down syndrome and other chromosomal disorders.
Non-invasive prenatal test assessing Down syndrome risk expands international reach
New prenatal test can detect trisomy 18 and trisomy 13.
Harmony prenatal test and Verifi test are competing closely to grab a handsome share of the total NIPT market.
Using that information, Natalie Vandemark of the University of Nebraska Medical Center in Omaha and her colleagues devised a prenatal test for the disorder.
New federal legislation aims to improve the information that expectant parents receive when a prenatal test is positive for conditions such as Down syndrome and spina bifida.
Advent of non-invasive prenatal test is poised to eliminate disadvantages associated with these methods, such as low rate of accuracy with maternal serum screening and NT scan, and risk of miscarriage with invasive amniocentesis and CVS procedures.