prenatal diagnosis


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pre·na·tal di·ag·no·sis

diagnosis using procedures available for the recognition of diseases and malformations in utero, and the conclusion reached.
Synonym(s): antenatal diagnosis

prenatal diagnosis

any of various diagnostic techniques to determine whether a developing fetus is affected with a genetic disorder or other abnormality. Such procedures as radiographic examination and ultrasound scanning can be used to follow fetal growth and detect structural abnormalities; amniocentesis enables fetal cells to be obtained from the amniotic fluid for culture and biochemical assay for detection of metabolic disorders and chromosomal analysis; fetoscopy enables fetal blood to be withdrawn from a blood vessel of the placenta and examined for disorders such as thalassemia, sickle cell anemia, and Duchenne's muscular dystrophy. If any of the test results are positive and the child is likely to be born with a severe defect or disease, the parents need support and advice from genetic counselors on whether to terminate the pregnancy. If the parents decide to have the baby, the nurse can help educate them about the specific disorder and prepare them for the special care required of a handicapped or genetically defective child. Also called antenatal diagnosis. See also chorionic villus sampling, genetic counseling, genetic screening.

prenatal diagnosis

Obstetrics The examination of fetal cells taken from the amniotic fluid, the primitive placenta–chorion, or umbilical cord for biochemical, chromosomal, or gene defects

pre·na·tal di·ag·no·sis

(prē-nā'tăl dī'ăg-nō'sis)
Diagnosis using procedures available for the recognition of diseases and malformations in utero, and the conclusion reached.

Prenatal diagnosis

The determination of whether a fetus possesses a disease or disorder while it is still in the womb.
References in periodicals archive ?
In this report, we have presented a case of the prenatal diagnosis of penoscrotal hypospadia using 2D and 3D US.
amniocentesis made actual prenatal diagnosis of some genetic disorders
iii) Prenatal diagnosis of genetic disorders and genetic counseling.
Case 4: This family had come for prenatal diagnosis of IP as their 5 yr old daughter was clinically suspected to have IP.
Thus, we could see conflicts over how information generated through Brownback-Kennedy is conveyed in the prenatal diagnosis setting.
PGD was developed as an alternative to prenatal diagnosis, where amniotic fluid (from the womb) is analysed when the foetus is about 16-weeks-old.
Modalities employed in the prenatal diagnosis of disease include the following:
Attitudes of people with physical disabilities toward genetic counseling and prenatal diagnosis have rarely been addressed in the literature.
He leads an internationally recognized research program in the following areas: lung development, congenital diaphragmatic hernia, fetal physiology, birth defects, prenatal diagnosis of surgical problems, fetal surgery, the genetic aspects of surgical disease, and fetal growth factors.
The license agreement grants Ikonisys a worldwide license under Abbott patents for the manufacture and sale of DNA probes in conjunction with Chromotest(TM), a revolutionary test for the prenatal diagnosis of chromosomal abnormalities using fetal cells from the maternal circulation.
A couple may opt for screening for one or several reasons: because the chance of being a carrier seems high to them, because they would consider prenatal diagnosis if they were shown to be carriers, or because results are usually reassuring.
Key Words: birth defects, cystic hygroma, pregnancy outcome, prenatal diagnosis