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prekallikrein |
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prekallikrein /pre·kal·li·kre·in/ (-kal-ĭ-kre´in) the proenzyme of plasma kallikrein; it is cleaved and activated by coagulation factor XII. prekallikrein [prekal′ikre′in] a plasma protein that is the proenzyme of plasma kallikrein. It is cleaved to its active enzyme form by activated coagulation factor XII. prekallikrein, n a plasma protein that is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. Prekallikrein deficiency leads to Fletcher factor deficiency, a congenital disease. prekallikrein fletcher factor in blood coagulation. Precursor of plasma kallikrein which circulates in the blood. Acts in the initiation of intrinsic coagulation. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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