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prekallikrein

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prekallikrein /pre·kal·li·kre·in/ (-kal-ĭ-kre´in) the proenzyme of plasma kallikrein; it is cleaved and activated by coagulation factor XII.
prekallikrein
[prekal′ikre′in]
a plasma protein that is the proenzyme of plasma kallikrein. It is cleaved to its active enzyme form by activated coagulation factor XII.

prekallikrein [pre-kal″ĭ-kre´in]
a plasma protein that is the proenzyme of plasma kallikrein; it is cleaved to its active enzyme form by activated coagulation factor XII.

prekallikrein,
n a plasma protein that is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. Prekallikrein deficiency leads to Fletcher factor deficiency, a congenital disease.

prekallikrein
fletcher factor in blood coagulation. Precursor of plasma kallikrein which circulates in the blood. Acts in the initiation of intrinsic coagulation.


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The assay of glandular kallikrein and prekallikrein human mixed saliva.
This test primarily monitors deficiencies in factors VIII, IX, XI, XII, prekallikrein and high molecular weight kininogen (HMWK).
Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.
 
 
 
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