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prehormone

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prehormone /pre·hor·mone/ (-hor´mōn) prohormone.
pre·hor·mone (pr-hôrmn)
n.
A glandular secretory product that is a precursor of a hormone but has little or no inherent biological potency itself.

prohormone [pro-hor´mōn]
a precursor of a hormone, such as a polypeptide that is cleaved to form a shorter polypeptide hormone or a steroid that is converted to an active hormone by peripheral metabolism. Called also prehormone.

prehormone
prohormone.


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Microbial immunologist Robert Modlin and colleagues found that macrophages (a type of white blood cell) increase their production of VDRs and an enzyme that converts the vitamin D prehormone into 1,25-D when the cells detect a pathogen.
Modlin's team showed that before making that antibiotic, those cells briefly boosted their production of vitamin D receptors and of an enzyme that converts the vitamin D prehormone into 1,25-D.
 
 
 
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