preemptive analgesia


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preemptive analgesia

Sensory blockade before incision Anesthesiology A pain control strategy intended to counteract central sensitization–'windup' or neuroplasticity, a 'physiologic' state of ↑ sensitization of excitable spinal neurons, coupled to a ↓ threshold for peripheral afferent pain terminals; PA combines local anesthetics, neuraxial blockade, and inhibition of mediators of windup to prevent self-perpetuating pain. See NMDA receptor antagonist, Windup. Cf Multimodality pain control.

preemptive analgesia

The administration of anesthetic before surgery in an attempt to abort postoperative pain and disability.
See also: analgesia
References in periodicals archive ?
New concepts in acute pain therapy: Preemptive analgesia.
Ninety men scheduled for radical prostatectomies (the complete surgical removal of the prostate gland) were assigned randomly to one of three groups: no preemptive analgesia, preemptive analgesia with a narcotic (fentanyl), and preemptive analgesia with a local anesthetic (bupivacaine).
Nasdaq: CPIX) today announced that Caldolor (ibuprofen) Injection is being used by anesthesiologists in a growing number of hospitals and surgery centers to provide preemptive analgesia for surgical patients.
Preemptive analgesia II: physiological pathways and pharmacological modalities.