precursor ion scan

precursor ion scan

In a multistage/mass spectrometry (MS/MS) experiment, mass-selected precursor ions are induced to dissociate into product ions, which are then mass analysed by a second analyser.

The precursor ion scan is one of three common scans in the single-step MS/MS experiment, in which a second mass analyser is set at the mass of the selected product ion; the first mass analyser is scanned from that mass upwards, resulting in a mass spectrum that contains signals for all the precursor ions that dissociate to the selected product ion.
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The analysis was performed in positive ion mode electrospray ion (ESI-MS) source and precursor ion scans m/z 264 and 282 and multiple reaction ion monitoring (MRM) mass transition m/z 564/282 (ceramides), and precursor ion scan m/z 184 lysophosphocholine (LPC), were used.
Precursor ion scan of m/z 184 in positive ion mode demonstrated no significant difference in lysophosphocholine (LPC) in adipose tissue of ob/ob and lean mice, irrespective of their diet (Fig.
Using precursor ion scan data to identify degradation candidates with subsequent confirmation by targeted SRM, both N- and C-terminal degradation products were identified (Fig.
During each infusion a precursor ion scan from m/z 900 to m/z 990 was performed (30-s integration).
Quantification was achieved by a precursor ion scan of m/z 184 specific for phosphocholine-containing lipids (22).
Data were acquired using a precursor ion scan of m/z 85 product ions over the range m/z 160-210.
They include product ion scans to detect expected metabolites, as well as precursor ion scans and neutral loss scans to detect both expected and unexpected metabolite ions.