precursor cell


Also found in: Wikipedia.

precursor cell

a population of cells in the bone marrow that are incapable of self-renewal; they are derived from progenitor cells and are the first cells of a particular blood cell line that can be recognized due to their specific morphologic characteristics (e.g., proerythroblast).
References in periodicals archive ?
I propose to replenish the tissue-specific precursor cell pool by directly programming local somatic cell types into relevant precursors.
The benefits derived from acquiring the approved and late-phase MSC products include: *near term launch of a mesenchymal lineage product in major jurisdictions; *broadened late -phase clinical programs in strategic areas of focus; and *leveraged roll out of infrastructure, skills and expertise needed to commercialize Mesenchymal Precursor Cell (MPC) products Mesoblast said.
Japanese patent number 5265190 provides Mesoblast with exclusive commercial rights in Japan through to September 2025 to all compositions-of-matter and uses of its Mesenchymal Precursor Cell (MPC)technology platform, irrespective of the MPC tissue source, including bone marrow, adipose, placenta, umbilical cord and dental pulp.
Mesoblast's off-the-shelf, allogeneic, Mesenchymal Precursor Cell (MPC) product for Type 2 diabetes is the first of the company's suite of biologic therapies to be delivered via a simple intravenous injection.
MELBOURNE, Australia, July 21, 2010 /PRNewswire/ -- Australian regenerative medicine company, Mesoblast Limited (ASX:MSB; ADR:MBLTY), today announced that the Australian Therapeutic Goods Administration (TGA) has issued a licence to Mesoblast to manufacture and supply its proprietary Mesenchymal Precursor Cell (MPC) products.
Working in the laboratory, the scientists found that in the absence of Wnt-10b both types of mouse precursor cell turned into fat.
Loring called the creation of the successful neural precursor cell line a "happy accident.
Melbourne, Australia, Nov 22, 2011 - (ABN Newswire) - Global regenerative medicine company, Mesoblast Limited (ASX:MSB), today announced that it has reached agreement with the United States Food and Drug Administration (FDA) on the key elements of the company's first clinical trial using intravenous delivery of its proprietary allogeneic, or off-the-shelf, mesenchymal precursor cell (MPC) technology in patients with Type 2 Diabetes.
ACE-536 promotes late-stage erythrocyte precursor cell differentiation, distinct from erythropoietin which acts during early, proliferative stages of erythropoiesis.
The constructs will be transformed into conditionally immortalized muscle precursor cell lines developed in the host lab.
Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.
I look forward to working closely with management and the Board to realize the value of OvaScience's egg precursor cell platform to generate new product opportunities.