preclinical

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preclinical

 [pre-klin´ĭ-k'l]
before a disease becomes clinically recognizable.

pre·clin·i·cal

(prē-klin'i-kăl),
1. Before the onset of disease.
2. A period in medical education before the student becomes involved with patients and clinical work.

preclinical

/pre·clin·i·cal/ (-klin´ĭ-k'l) before a disease becomes clinically recognizable.

preclinical

(prē-klĭn′ĭ-kəl)
adj.
Of or relating to the period of a disease before the appearance of symptoms.

preclinical

[-klin′ikəl]
Etymology: L, prae + Gk, kline, bed
a stage in a disease when a specific diagnosis cannot be made because adequate signs and symptoms have not yet developed.

pre·clin·i·cal

(prē-klin'i-kăl)
1. Before the onset of disease.
2. A period in medical education before the student becomes involved with patients and clinical work.

preclinical

1. Pertaining to the incubation period of a disease or to the period before signs and symptoms occur.
2. The period of training of a medical student in the basic medical sciences before access to patients is allowed.

preclinical

before a disease becomes clinically recognizable.
References in periodicals archive ?
SysMedPD unites a highly experienced multidisciplinary consortium in an ambitious project to develop and apply a systems biomedicine approach to preclinically identify candidate neuroprotectants, for the estimated 1-2 million people worldwide who suffer from PD with mitochondrial dysfunction.
ImmunoGen's SAR3419 was licensed to Sanofi preclinically as part of a broader collaboration between the companies.
Preclinically, it has shown anti-inflammatory (Roberto et al.
In the HIV development program a number of deuterium modified-versions of atazanavir were evaluated preclinically, and a subset was selected for further testing in early human clinical studies.
EFLA [R]943, a stable Olive leaf extract which is standardized to oleuropein, has been preclinically studied for its safety and anti-hypertensive effects (Khayyal et al.
Inhibition of BACE1( -secretase) is a preclinically validated disease-modifying target in AD.
SAR3419, created by ImmunoGen and preclinically licensed to Sanofi SA (EPA:SAN) within a broader collaboration between the companies, is a potential new treatment for CD19+ non-Hodgkin's lymphoma (NHL) and other B-cell malignancies.
The effect of mistletoe extracts on leukaemia and lymphoma is a further focal point, where again the use of mistletoe extracts showed no risks clinically and preclinically.
Preclinically, ASG-22ME has demonstrated potent antitumor activity, including regressions in models of established breast, bladder and lung cancer.
Dror Harats, chief executive officer of VBL Therapeutics, said that building on the promising results observed preclinically and the success of the company's four separate Phase I clinical studies, VBL Therapeutics is excited to advance VB-201 into Phase II development for psoriasis.
STA-9090 is a second-generation, synthetic, small-molecule Hsp90 inhibitor that has shown potent and selective activity preclinically and is currently in Phase 2 trials in a number of indications.
Pharmacokinetic data indicate that blood levels have been achieved that surpass those predicted preclinically to be associated with complete inhibition of all resistant mutants.