precipitin test


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precipitin

 [pre-sip´ĭ-tin]
an antibody to antigen that specifically aggregates the antigen in vivo or in vitro to give a visible precipitate.
precipitin reaction a reaction involving the specific serologic precipitation of an antigen in solution with its specific antiserum in the presence of electrolytes. The reaction is used in the typing of pneumococcus strains, in testing whether blood is human or animal, and for diagnostic purposes.
precipitin test any test in which the positive reaction consists of the formation and deposit of a precipitate in the fluid being tested. See also precipitin reaction.

pre·cip·i·tin test

an in vitro test in which antigen is in soluble form and precipitates when it combines with added specific antibody in the presence of an electrolyte.
See also: gel diffusion precipitin tests, ring precipitin test.
Synonym(s): precipitation test

pre·cip·i·tin test

(prĕ-sip'i-tin test)
An in vitro procedure in which antigen is in soluble form and precipitates when it combines with added specific antibody in the presence of an electrolyte.
See also: gel diffusion precipitin tests

precipitin test

A test in which two dissolved substances in a solution join to form a visible solid. The results depend on the strength of the attraction between the Fab fragment on the antibody and the corresponding epitope on the antigen (affinity) and on the stability of the complex (antibody avidity). The test demonstrates how immune complexes form in the circulation and are deposited in blood vessel walls. See: precipitation test