pre-eclampsia

(redirected from pre-eclamptic)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to pre-eclamptic: preeclampsia

eclampsia/pre-eclampsia

(From Greek eklampsis, shining forth) Metabolic toxemia of pregnancy Obstetrics A condition which usually develops in late pregnancy or the immediate puerperium Clinical HTN, hemoconcentration, sodium retention with resultant edema Lab Albuminuria, proteinuria, hypoproteinemia, ↑ nitrogen/BUN; pre-eclampsia is most common in primigravidas, after the 24th gestational wk, but may occur as soon as trophoblastic tissue is present Treatment If mild, bed rest and sedation; if severe, antihypertensives–eg, vasodilators, α methyldopa; if convulsions, magnesium sulfate. See HELLP syndrome.

pre-eclampsia

A syndrome of high blood pressure (HYPERTENSION), fluid accumulation in the tissues (OEDEMA) and protein in the urine (albuminuria) that becomes apparent in the second half of pregnancy. Pre-eclampsia is primarily a placental disorder with damage to the inner lining (endothelium) of placental blood vessels. Oxygen FREE RADICALS cause endothelial cell damage, and may lead to reduced NITRIC OXIDE production, so that blood vessel widening (vasodilatation) is interfered with. Pre-eclampsia is a warning of the dangerous complication of ECLAMPSIA-a condition of seizures carrying a high maternal and fetal mortality. A major reason for antenatal care is to monitor for pre-eclampsia and to treat the condition, induce labour or perform a Caesarean section. It has been shown that abnormally high levels of circulating angiogenic factors such as vascular endothelial growth factor and soluble fms-like tyrosine kinase 1 predict the development of pre-eclampsia.
References in periodicals archive ?
The assessment of placental volume and mean gray value in pre-eclamptic placentas by using three-dimensional ultrasonography.
Study group involved 94 healthy normotensive pregnant women (systolic blood pressure less than 130 mmHg and diastolic blood pressure less than 85 mmHg) with uncomplicated pregnancy and 97 pre-eclamptic patients.
The anaesthetic management in pre-eclamptic patients is important, and should start with a detailed pre-anaesthetic assessment.
Compared to women in their third trimester of a normal pregnancy, pre-eclamptic women had a similar apnoea-hypopnoea index but were spending twice as much time with inspiratory flow limitation (106).
1994), and plasma levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthesis, increase in pre-eclamptic patients (Fickling et al.
Her previous pre-eclamptic pregnancy and diabetes gave rise to real concerns about increased vascular resistance and we understood that if we removed excessive fluid we would reduce the size of the vascular bed, thus increasing Karen's BP while reducing the available fluid for the baby.
Baby Scott was born on Sunday when doctors performed an emergency Caesarean section after mum Rachel Smith suffered a dangerous pre-eclamptic pregnancy.
Serum cystatin C reflects glomerular endotheliosis in normal, hypertensive and pre-eclamptic pregnancies.
The results showed that PIGF levels were far lower in pre-eclamptic patients.
The results showed that PIGF levels were dramatically lower in pre-eclamptic patients, both at the time they were ill and six to eight weeks before any symptoms appeared.
Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women.