Pranlukast | definition of pranlukast by Medical dictionary
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pranlukast Singulair® Allergy medicine An antileukotriene that ↓ early and late response inflammation and bronchoconstriction of asthma Effect Improved FEV1, peak expiratory flow rate, Sx–eg, night awakening, ↓ use of β2 agonists Mechanism LTD4 receptor antagonism; pranlukast is used for asthma prophylaxis; it ↓ bronchial hyperresponsiveness in chronic asthma Adverse effects Zafirkulast ↑ in PT in Pts on warfarin. See Antileukotrienes, Asthma.
References in periodicals archive
Churg-Strauss syndrome after corticosteroid withdrawal in an asthmatic patient treated with pranlukast
Asthma - SB's pranlukast
, the world's first leukotriene