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pramlintide

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pramlintide,
an antidiabetic that modulates and slows stomach emptying, prevents postprandial rise in plasma glucagon, decreases appetite, and leads to decreased caloric intake and weight loss.
indications This drug is used as an adjunct to insulin therapy to treat uncontrolled type 1 or type 2 diabetes.
contraindications Gastroparesis and known hypersensitivity to this drug or to metacresol prohibit its use.
adverse effects Adverse effects of this drug include headache, fatigue, dizziness, nausea, vomiting, anorexia, abdominal pain, injection site reactions, hypoglycemia (while used with insulin), arthralgia, cough, pharyngitis, and systemic allergy.

pramlintide
Endocrinology An amylin analogue of possible use in ↑ glucose control in Pts with DM. See Diabetes mellitus.


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5 million in private investments, enough to press on with pramlintide and a second diabetes drug it was developing.
In July 2009, Amylin presented phase II data from a phase II study in 149 patients testing pramlintide / metreleptin vs.
Amylin's pramlintide acetate (Symlin) recently received approval as an adjunct therapy in combination with insulin for patients with type 1 diabetes.
 
 
 
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