pramipexole


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pramipexole

 [pram″ĭ-pek´sōl]
a dopamine agonist used in the form of the dihydrochloride salt in treatment of parkinson's disease, administered orally.

pramipexole

/pram·i·pex·ole/ (pram″ĭ-pek´sōl) a dopamine agonist used in the form of the dihydrochloride salt as an antidyskinetic in the treatment of Parkinson's disease.

pramipexole

(prăm′ə-pĕk′sōl′)
n.
A dopamine agonist used in the treatment of Parkinson's disease.

pramipexole

an antiparkinson agent.
indication It is used to treat parkinsonism.
contraindication Known hypersensitivity prohibits its use.
adverse effects Life-threatening effects are hemolytic anemia, leukopenia, and agranulocytosis. Other adverse effects include psychosis, hallucination, depression, dizziness, constipation, impotence, and blurred vision. Common side effects include agitation, insomnia, nausea, anorexia, and orthostatic hypotension.

pramipexole

Mirapex® Neurology A dopamine antagonist used to manage Parkinson's disease Adverse effects Constipation, dry mouth, vision defects, insomnia
References in periodicals archive ?
Pramipexole is a dopamine agonist that has been approved by the FDA for the treatment of restless legs syndrome.
A 6-month double-blind study of 234 patients using pramipexole found that 9.
While both iron and pramipexole are established treatments for restless legs syndrome (RLS), the new study (n = 30) was the first randomized trial to compare them head to head.
For instance, in October 2012, Boehringer-Ingelheim and the Institute of Drug Technology (Farmanguinhos) agreed on a partnership for the local production of Pramipexole for Parkinson's disease treatment.
Effect of pramipexole on cutaneous-silent-period parameters in patients with restless legs syndrome.
Thirty-six were on 1 or more concurrent antiparkinsonian medications (carbidopa/levodopa [n=27], pramipexole [n=3], selegiline [n=2], pramipexole and selegiline combined [n=4]).
While these medications remain the mainstay of general FS treatment, health care professionals occasionally prescribe several other drugs for the treatment of particular FS-associated conditions: pramipexole (Mirapex) for restless legs syndrome, gabapentin (Neurontin) for nerve pain and tizanidine hydrochloride (Zanaflex) for muscle spasm.
Symptom improvement, as measured by the International Restless Legs Syndrome Rating Scale of severity, was significantly greater for the pramipexole group compared to the placebo group.
Eight of the patients were taking a dopamine agonist called pramipexole and the ninth was on another drug, pergolide.
CANADA--Two dopamine agonists, pramipexole (Miapex) and ropinirole (Requip), may be responsible for excessive sleepiness in patients with Parkinson's disease.
The three most often used in the United States would be pergolide (Permax), pramipexole (Mirapex), and ropinirole (Requip).
The dopamine agonist pramipexole staved off three motor complications longer than levodopa in a double-blind, placebo-controlled trial in patients with early Parkinson's disease, according to Dr.