pral·i·dox·ime chlor·ide(pral'i-dok'sēm klōr'īd, prā-li-),
Used to restore the inactivated cholinesterase activity resulting from organophosphate poisoning; has some limited value as an antagonist of the carbamate type of cholinesterase inhibitors that are used in the treatment of myasthenia gravis.
a cholinesterase reactivator.
indications It is prescribed as an antidote for organophosphate poisoning and drug overdosage in the treatment of myasthenia gravis.
contraindications Known hypersensitivity to this drug prohibits its use. It is contraindicated in poisoning by carbamate insecticides that react with pralidoxime.
adverse effects Among the most serious adverse effects are dizziness, tachycardia, hyperventilation, and muscle weakness. These reactions are most common when the drug is injected too rapidly.
pral·i·dox·ime chlor·ide(pral'i-dok'sēm klōr'īd)
A chloride salt of the oxime pralidoxime; the salt is used as an antidote in cases of poisoning by organophosphorous anticholinesterases (including organophosphorous pesticides and nerve agents).
A cholinesterase reactivator used in treating poisoning due to certain pesticides or drugs with anticholinesterase activity.