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pralidoxime chloride

   Also found in: Wikipedia 0.01 sec.
pralidoxime chloride
[pral′ədok′sēm]
a cholinesterase reactivator.
indications It is prescribed as an antidote for organophosphate poisoning and drug overdosage in the treatment of myasthenia gravis.
contraindications Known hypersensitivity to this drug prohibits its use. It is contraindicated in poisoning by carbamate insecticides that react with pralidoxime.
adverse effects Among the most serious adverse effects are dizziness, tachycardia, hyperventilation, and muscle weakness. These reactions are most common when the drug is injected too rapidly.


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Two drugs,atropine and pralidoxime chloride,have been used by the military as antidotes for nerve agent poisoning.
Police get nerve gas attack antidotes by Daily Post (Liverpool, England)
The nerve gas antidotes include Atropine Sulfate (atropen), Pralidoxime Chloride (combopen), Diazepam and Morphine Sulfate.
Nerve gas antidote manufacturer nets 483 for aseptic deficiencies by Inspection Monitor
King plans to submit applications to the DHS for other similar auto-injector technologies: DuoDote([TM]) (single, dual-chambered auto-injector containing two separate antidotes for organophosphorus poisoning, atropine and pralidoxime chloride); and the Mark I[TM] Nerve Agent Auto-Injector Kit (two separate auto-injectors, one containing atropine and one containing pralidoxime chloride, both antidotes for organophosphorus poisoning).
King Pharmaceuticals Receives DHS Safety Act Designation and ... by Business Wire
 
 
 
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