Unusual disseminated lesions of poxvirus
in psittacines resembling canary pox.
Tony Sainsbury, who is a lecturer in wild animal health at the Zoological Society of London, added: "The cases seen by ZSL's national red squirrel disease surveillance programme clearly demonstrate the severity and debilitating nature of the squirrel poxvirus
disease on red squirrels.
Molecular characterization of reticuloendotheliosis virus insertions in the genome of field and vaccine strains of fowl poxvirus
People have been looking for the poxvirus
receptors for years and years," says Grant McFadden of the University of Western Ontario in London.
Grey squirrels threaten the existence of red squirrels because of the squirrel poxvirus
they carry, which affects the native species because few have protection against the virus.
She is interested in poxvirus
diagnosis and surveillance and has developed kits for detecting poxviruses
(genus Avipoxvirus, family Poxviridae) is an enveloped double-stranded DNA virus that may be transmitted to birds by arthropod vectors or mucosal membrane contact with infectious particles.
The vaccinia poxvirus
strain backbone of JX-594 has been used safely in millions of people as part of a worldwide vaccination program.
She returned to the United States and presented with tenderness of the nodules and mild local adenopathy; the differential diagnosis included tropical ulcer, atypical mycobacterial infection, fungal infection, cutaneous anthrax, and poxvirus
infection, which was the diagnosis confirmed by the CDC.
After a typical poxvirus
cytopathic effect was observed, virus was plaque purified and placed on Vero cell monolayers for viral amplification.
Electron microscopy confirmed the presence of poxvirus
in inclusions in the first case, and genetic analysis of DNA extracted from both cases found an identical viral genome that differs from all other known poxviruses
The Company's lead initiative is its Smallpox Biodefense Therapeutic that has been shown to neutralize poxvirus