potentiate


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

potentiate

(pə-tĕn′shē-āt′)
tr.v. potenti·ated, potenti·ating, potenti·ates
To make (something, especially a drug or a metabolic or chemical reaction) effective or more effective.

po·ten′ti·a′tion n.

potentiate

[pōten′shē·āt]
to increase the strength or degree of activity of something.

potentiate

(pō-tĕn′shē-āt)
To increase the potency or action.
References in periodicals archive ?
These pharmacological studies confirm our earlier published data that indiplon has the best combination of affinity and selectivity of the 'non-benzodiazepine' sleep agents reported to date to potentiate GABA-A receptors", said Alan C Foster, PhD, Neurocrine Fellow at Neurocrine Biosciences.
Oiethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of in vitro l-methyl-4-phenylpyridinium.
Other phytochemicals in tomato may act in synergy with lycopene to potentiate protective effects and to help in the maintenance of prostate health.
These results suggest that arsenite might potentiate vasoconstriction by enhancing the [Ca.
Some crack cocaine users may lace the drug with rat poison to potentiate its effects, which can lead to severe coagulopathy, reported Dr.
Our goal in using ECT is to potentiate the process that ends the seizure.
These products have been shown to potentiate the hypotensive effects of nitrate drugs such as NitroMist([TM]).
To achieve these goals, liposomal, polymeric and micellar corticosteroids, several different animal models, and several different imaging agents and techniques will be used to (I) visualize and optimize nanomedicine-mediated vascular normalization; to (II) potentiate chemotherapy; and to (III) potentiate radiotherapy.
BROVANA, as with other long-acting beta2-adrenergic agonists, should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors, tricyclic antidepressants, or drugs known to prolong the QTC interval because these agents may potentiate the action of adrenergic agonists on the cardiovascular system.
The preclinical study, presented by Dr D Banerjee from the Cancer Institute of New Jersey, USA, indicated that in human leukaemia or lymphoma cell lines Aplidin can potentiate the effect of three standard drugs for these conditions (doxorubicin, methotrexate and cytosine arabinoside) by making the cells more sensitive to treatment at lower drug concentrations.
Highlights of the meeting include: * Selective GSK3 Inhibitors Potentiate Insulin Activation of Glucose Transport CHIRON CORPORATION * The Development of Tarceva (OSI-774): An Orally-Active EGFR Inhibitor OSI PHARMACEUTICALS * The Platelet-Derived Growth Factor Receptor (PDGFR) Family as Therapeutic Targets COR THERAPEUTICS
Ampligen(R), an experimental immune therapeutic, is being developed to potentiate conventional cell based human vaccines, including avian influenza vaccines.