Subsequently, neurotransmitter is released into the synaptic cleft and diffuses to the postsynaptic membrane
to activate neurotransmitter receptors.
This balance can be maintained by regulating the number of neurotransmitter receptors in the postsynaptic membrane
Sufficient depolarization of the postsynaptic membrane
reaches a threshold at which a second action potential is induced and the impulse is successfully transmitted to the next neuron.
The depolarizing agents bind to acetylcholine receptors and cause a sustained postsynaptic membrane
Following nerve impulse transmission, acetylcholine is released from the postsynaptic membrane
receptor and is broken down by acetylcholinesterase (AChE) to choline and acetic acid.
Direct receptors are known as ionotropic because they are linked to ion channels, pores in the postsynaptic membrane that allow passage of ions when opened.
1A] is both an autoreceptor on the neuronal cell body and a postsynaptic membrane receptor that reduces adenylyl cyclase activity.
NMDARs and nNOS are coupled together at the postsynaptic membrane
through their interaction with postsynaptic density protein (PSD) 95 via PSD-95/disc large/zonula occludens-1 (PDZ) domains.
A neuromuscular junction is comprised of three components--the presynaptic membrane, the synaptic cleft, and the postsynaptic membrane
These presynaptic and postsynaptic membrane
changes occur in response to mediators which are initiated by the postsynaptic membrane
GABA is an inhibitory neurotransmitter and the binding of GABA to its receptors in the central nervous system can lead to an influx of chloride ion to the neurons and hyper polarization of pre- and postsynaptic membranes
A] receptors are present both at the synapse and on postsynaptic membranes
distant from synapses.