These cortical developmental anomalies can be grouped into three categories: 1) abnormal proliferation of neurons and glia; 2) abnormal migration of postmitotic
neurons to the cortical plate; and 3) abnormal cortical organization and elaboration of connections.
Mitochondrial turnover and aging of long-lived postmitotic
cells: the mitochondrial-lysosomal
Pre-study has reported caspase-3 is expressed in postmitotic
dopaminergic neurons and caspase-3 activation could result in dopaminergic neuronal apoptosis in PD model, which may represent a common integration point and constitute an attractive target for antiapoptotic therapy in PD (Hartmann et al.
Pre- and postmitotic
reorientation of microtubule arrays in young Sphagnum leaflets: transitional stages and initiation sites.
Despite its significance to basic research as well as its potential medical implications, postmitotic
chromatin decondensation is only poorly understood.
Cell cycle patterns and estimates of in situ division rates of dinoflagellates of the genus Dinophysis by a postmitotic
DNMTs are abundantly expressed in postmitotic
nerve cells (i.
Cameron IL, Smith KR, Pool TB, Element concentration changes in mitotically active and postmitotic
entrocytes: an X-ray microanalysis study, J.
2) Lipofuscin is a pigmented membrane-bound waste product that accumulates in postmitotic
Protection of neurons against PBDE-induced cytotoxicity by the presence of astrocytes is thus the probable reason for differentiated hNPC insensitivity toward PBDE-dependent cell death, whereas proliferating precursors are known to possess better defense mechanisms than do postmitotic
neural cells (Madhavan et al.
They concluded that CD133 and CD15 can be used as selectable markers, but CD24 coexpression helps to distinguish foetal mouse multipotent stem cells from neuronal progenitors and postmitotic
Sox2 is expressed in cells that retain their ability to proliferate and/or acquire glial fates, whereas it is down-regulated in cells that become postmitotic
and differentiate into neurons (Bylund et al.