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postantibiotic effect

    0.01 sec.
postantibiotic effect
the period after antibiotic serum levels have dropped below the minimum inhibitory concentration when no bacterial growth occurs.


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At lower concentrations, bacteria were significantly inhibited, with a clear postantibiotic effect even at such a low dose as 0.
In addition to high concentrations of fluoroquinolone, which trigger the secondary bactericidal mechanism, higher concentrations at DNA targets also play a role in the emergence of resistance because the postantibiotic effect of the fluoroquinolones is dependent upon concentration, time, and the microorganism.
13,14) Furthermore, evidence suggests that the postantibiotic effect is potentiated by increased antibiotic concentrations up to 10 times the minimum inhibitory concentration.
 
 
 
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