positive inotropic agent

positive inotropic agent

Cardiology An agent–eg, digoxin, gitalin, lanatoside, beta-adrenoceptor agonists that ↑ force and velocity of myocardial contractility
References in periodicals archive ?
Istaroxime is a potent positive inotropic agent that increases myocardial contractility through inhibition of Na+/K+-ATPase.
As such, our study results seem to suggest that determination of baseline IGF-I levels may help guide clinicians when making the decision to administer a positive inotropic agent such as levosimendan in patients admitted with a diagnosis of decompensated HE In this study, we only assessed short-term response to levosimendan treatment.
A positive inotropic agent that simultaneously activates intracellular [K.
When intravenous vasoactive medications are required for acute decompensated heart failure, patients who receive a vasodilator or natriuretic peptide are more likely to survive than are those who receive a positive inotropic agent, reported William T.
This herb is a positive inotropic agent that increases contractility of the heart," said Dr.
Pimobendan is a phosphodiesterase III inhibitor and calcium channel sensitizer causing a inodilating effect, at reduced myocardial oxygen consumption energy expenditure when compared to other positive inotropic agents as indicated by Fuentes, 2004 and Atkinson et al.
Temporary therapeutic measures include rapid fluid infusion, administration of positive inotropic agents, and pericardiocentesis.
New positive inotropic agents with higher safety margins and stronger effects on cardiac contractility have been introduced in human and veterinary cardiology during the last 20 years (3) and their use must be explored in the avian patient.
For cardiologists, internists, and others, specialists from the US, India, and Guatemala emphasize advances in the understanding of coronary circulation, the molecular mechanisms of myocyte function, and the assessment of regional and global ventricular functions in physiologic and pathologic conditions, and address advances in cardiovascular pharmacology, including the advantages and disadvantages of diuretic therapy, vasodilators, neurohormone modulators, positive inotropic agents, and antilipid, antithrombotic, and antiplatelet agents, and their clinical pharmacology in the management of various cardiovascular disorders.
5) For those persons with advanced HF or ADHF, tailored therapy often includes the addition of positive inotropic agents such as dobutamine.
The relevant markets in which overlaps occurred were found to be for vitamin B12 in France, positive inotropic agents in the United Kingdom and Belgium, cerebral and peripheral vasotherapeutics in Ireland, topical varicose therapy in Italy, macrolides and similar types in France, glycopeptide antibiotics also in France, specific anti-rheumatics in Portugal, muscle relaxants also in Portugal, hypnotics and sedatives in Greece, Ireland, Luxembourg and Sweden, heparins and heparinoids in Germany, Austria, Belgium, Spain, Finland, France, Italy, Luxembourg, the Netherlands, Portugal and the United Kingdom, and treatment of colorectal cancer in France, Germany, Italy, the Netherlands, Spain, Sweden and the United Kingdom.
If hypotension occurs, treat initially by slowing the infusion; additional standard therapy may be needed, including the following: vasopressor drugs, positive inotropic agents, and volume expansion.

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