portal of entry


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portal of entry

the route by which an infectious agent enters the body, such as through nonintact skin.

por·tal of en·try

(pōr'tăl en'trē)
Refers to the process whereby a pathogen enters the body, gains access to susceptible tissues, and causes disease or infection (e.g., direct contact, ingestion, inhalation).

por·tal of en·try

(pōr'tăl en'trē)
Refers to the process whereby a pathogen enters the body, gains access to susceptible tissues, and causes disease or infection.

portal of entry,

n the area in which a microorganism enters the body. They may be cuts, lesions, injection sites, or natural body orifices.

portal

1. an avenue of entrance; porta.
2. pertaining to an entrance, especially the porta hepatis.

portal-azygos anastomosis
a form of portacaval shunt with the portal vein bypassing the liver and emptying directly into the azygos vein.
portal biliary bacterial circulation
a continuous normal circulation of bacteria brought to the liver in the portal vein from the gut and excreted back into the gut via the biliary system.
portal canal
tissue space situated between three or more hepatic lobules; carries the blood and lymphatic vessels and connective tissue.
portal-caval
see portacaval.
portal circulation
circulation of blood from the capillaries of one organ to those of another; applied especially to the passage of blood from the gastrointestinal tract and spleen through the portal vein to the liver. See also circulatory system.
portal of entry
the pathway by which bacteria or other pathogenic agents gain entry to the body.
portal fibrosis
see biliary fibrosis.
portal hypertension
see portal obstruction.
portal obstruction
obstruction of portal venous blood flow through external pressure on the portal vein, by abscess or tumor or by hepatic fibrosis constricting the hepatic vascular bed, causes interference with digestion and absorption and eventually venous return so that ascites and diarrhea develop.
portal system
an arrangement by which blood collected from one set of capillaries passes through a large vessel or vessels and another set of capillaries before returning to the systemic circulation, as in the pituitary gland and liver.
Includes the hepatic portal system consisting of portal vein and its tributaries from the stomach, intestine, pancreas and spleen, the vessels into which the portal vein divides in the liver and the hepatic veins that enter into the caudal vena cava.
portal systemic shunt
see portacaval shunt.
portal triad
anatomically close association of interlobular bile duct, branches of hepatic artery and portal vein.
portal vascular anomalies
see portacaval anastomosis.
portal vein
a short, thick trunk formed by the union of the caudal mesenteric and splenic veins; at the porta hepatis, it divides into successively smaller branches, following branches of the hepatic artery, until it forms a capillary system of sinusoids that permeates the entire substance of the liver.
portal vein obstruction
acute, complete obstruction causes a syndrome similar to that of intestinal obstruction without signs suggesting liver involvement; partial occlusion causes shrinkage and eventual atrophy of the relevant section of the liver.
portal vein rupture
rare complication of epiploic foraminal herniation; sudden death from internal hemorrhage results.
portal venule absence
a congenital defect resulting in the development of multiple shunts within the liver, hepatoportal fibrosis and ascites, general immaturity and hepatic encephalopathy.
References in periodicals archive ?
We observed an increase in the incidence of IF over time among patients in the hematology ward of our hospital; a cutaneous portal of entry was evident in most cases.
13] Three cases in this study were felt to have a gastrointestinal portal of entry, and intestinal colonization as a predisposition to infection has been referred to elsewhere.
The order of portal of entry for this study contrasts with urinary tract, wound, and respiratory tract for one study of hospital-acquired Klebsiella bacteremia [11] and with urinary tract, lung, abscess or wound, and upper respiratory tract for a study of gram-negative bacteremia in a university hospital.
The first and the longest branch had its portal of entry through anterior substance of the kidney midway between the upper pole and upper part of the hilum.
The skin of carp acts as the portal of entry of CyHV-3 and the site of early replication (29).
We really need to emphasize thatintravenous drug use is the major portal of entry of the [AIDS] virus into the heterosexual population,' says Neal Steigbigel of the Montefiore Medical Center in Bronx, N.
Some strains of HIV use the CXCR4 co-receptor as a portal of entry either exclusively or in addition to CCR5.
Inoculation eschars occur at the sites of tick bites and consist of a focus of epidermal and dermal necrosis [approximately equal to] 1 cm in diameter; they represent the portal of entry of the infectious agent into the host and the first site of challenge between the infected human host and the bacterium.
The portal of entry of the ameba may be a break in the skin or the respiratory tract by inhalation of wind-blown cysts, with subsequent spread to the CNS through the circulatory system (1).
Nasdaq: PGNX) announced that it is today initiating a phase 1b clinical trial of a new investigational HIV therapy - a humanized monoclonal antibody that specifically binds CCR5, a receptor that serves as a portal of entry for HIV into cells of the immune system.
In our patient, we were unable to determine the portal of entry and the sequence of fungal dissemination; no skin lesions were present at the time of admission.
The CCR5 co-receptor is a key portal of entry used by HIV to infect immune system cells; therefore, blocking this molecular doorway represents an important therapeutic target.