port-wine stain

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Related to port-wine stain: nevus flammeus, Port Wine Nevus


1. a substance used to impart color to tissues or cells, to facilitate microscopic study and identification.
2. an area of discoloration of the skin.
acid-fast stain a staining procedure for demonstrating acid-fast microorganisms.
differential stain one that facilitates differentiation of various elements in a specimen.
endogenous stain an intrinsic stain acquired during tooth development.
exogenous stain an intrinsic stain acquired after a tooth has erupted.
extrinsic stain a stain that can be removed from a tooth surface by polishing.
Giemsa stain a solution containing azure II-eosin, azure II-glycerin, and methanol; used for staining protozoan parasites such as Plasmodium and Trypanosoma, for Chlamydia, for differential staining of blood smears, and for viral inclusion bodies. Stained elements appear pink to purple to blue.
Gram stain a staining procedure in which bacteria are stained with crystal violet, treated with strong iodine solution, decolorized with ethanol or ethanol-acetone, and counterstained with a contrasting dye; those retaining the stain are called gram-positive, and those losing the stain but staining with the counterstain are called gram-negative.
hematoxylin and eosin stain a mixture of hematoxylin in distilled water and aqueous eosin solution, employed universally for routine examination of tissues.
intrinsic stain a stain that is within the enamel of a tooth and cannot be removed by polishing.
metachromatic stain one that produces in certain elements a color different from that of the stain itself.
nuclear stain one that selectively stains cell nuclei, generally a basic stain.
port-wine stain a persistent dark red to purple nevus flammeus that grows proportionately with the affected child and is usually found on the face. Initially it is macular, but the surface may develop angiomatous overgrowths with time. Port-wine stains often occur in association with other congenital abnormalities.
supravital stain a stain introduced in living tissue or cells that have been removed from the body.
tumor stain an area of increased density in a radiograph, due to collection of contrast material in distorted and abnormal vessels, prominent in the capillary and venous phases of arteriography, and presumed to indicate neoplasm.
vital stain a stain introduced into the living organism, and taken up selectively by various tissue or cellular elements.
Wright's stain a mixture of eosin and methylene blue, used for demonstrating blood cells and malarial parasites.

ne·vus flam·'me·us

, flame nevus
a large congenital vascular malformation nevus having a purplish color; it is usually found on the head and neck and persists throughout life.
See also: Sturge-Weber syndrome.
Synonym(s): port-wine stain

port-wine stain

A common congenital neurovascular malformation, appearing as deep red-purple macular lesions, corresponding to cutaneous angioma(s), often located in the ophthalmic branch of the trigeminal nerve; when located on the meninges, port-wine nevi may be confined to the occipitoparietal pial vessels, where sluggish blood flow predisposes to hypoxia of underlying cortex; port-wine nevi may occur in the normal population—e.g., Mikhail Gorbachev—or be part of various syndromes—e.g., Klippel-Trenaunay, Beckwith-Wiedemann, Cobb, Rubenstein-Taybi, trisomy 13 syndromes
Management Flashlamp-pulsed tunable argon dye laser, most effective if administered < age 7. More treatment may be required for facial lesions

port-wine stain

A flat, permanent, purple-red birthmark caused by a benign tumour of small skin blood vessels. A capillary HAEMANGIOMA. Port-wine stains can be treated by skin grafting or with laser burns.


benign, localized, overgrowth of skin melanocytes or blood vessels (see ABCDE)
  • naevus pigmentosus; mole congenital, raised/sessile, pigmented, benign skin lesion

  • naevus pilosus hairy mole

  • naevus spilus; speckled lentiginous naevus small light brown macule, increasing in size over time to form a speckled benign lesion of up to 10cm diameter; it should be monitored as it may undergo malignant changes (see ABCDE)

  • spider naevus small skin area with visible local arteries, resembling a spider

  • strawberry naevus small, raised, vascular naevus, resembling a strawberry

  • vascular naevus; port-wine stain congenital, often widespread, red/purple discoloration of skin, caused by capillary hypertrophy

References in periodicals archive ?
With the discovery of the gene and pathway involved in SWS and port-wine stains, researchers can now begin investigating drugs that selectively inhibit the implicated pathways.
These children need not be scarred by the psychological impact of these lesions anymore," says Tan, who notes that children with port-wine stain often are shunned by other children.
Friedlander added that new research is investigating the use of an oral medication, rapamycin, for treating port-wine stains in conjunction with laser therapy.
Port-wine stains affect one in every 500 babies and occur when blood vessels in the affected skin lack the small nerve fibres which are necessary to narrow them.
IPL, which is derived from selective photothermolysis, utilizes a wide range of light wavelengths to treat a variety of skin conditions and aesthetic procedures, including spider veins, birthmarks, port-wine stains, acne scars, fine lines and wrinkles, and permanent hair reduction.
He was born with Sturge-Weber syndrome, a rare congenital neurological and skin disorder often associated with port-wine stains on the face, glaucoma and seizures.
Facial port-wine stains and associated leptomeningeal angiomas typify the vascular findings.