porphyrinogens

por·phy·rin·o·gens

(pōr'fi-rin'ō-jenz),
Intermediates in the biosynthesis of heme, as follows: four porphobilinogens condense to form uroporphyrinogens I and III (giving rise to side products uroporphyrins I and III) that are decarboxylated to form coproporphyrinogens I and III (giving rise to side products coproporphyrins I and III); coproporphyrinogen III is oxidized to protoporphyrinogen III (IX), which is then oxidized to form protoporphyrin III (IX) (this last intermediate adds ferrous iron to yield heme); certain porphyrinogens are elevated in certain porphyrias.

por·phy·rin·o·gens

(pōr'fir-in'ō-jenz)
Intermediates in the biosynthesis of heme; certain porphyrinogens are elevated in certain porphyrias.

por·phy·rin·o·gens

(pōr'fir-in'ō-jenz)
Intermediates in the biosynthesis of heme.
References in periodicals archive ?
Porphyrinogens are the building blocks of all the hemoproteins, such as hemoglobin and the cytochrome enzymes.
There are several mechanisms that may operate to make fecal porphyrin recovery an unreliable marker of biliary porphyrin excretion (9, 24), including variable oxidation of porphyrinogens to the corresponding porphyrins, variable reabsorption and an enterohepatic cycling of porphyrins (27, 28), the effects of microbial porphyrin metabolism within the bowel (8, 29-31), and differences in the methodologies used for recovery of fecal porphyrins.
Bile porphyrin and porphyrinogen levels in erythropoietic protoporphyria and variegate porphyria.