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porphyrinogen

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porphyrinogen /por·phy·rin·o·gen/ (por″fĭ-rin´o-jen) the reduced form of any porphyrin; they are the functional intermediates in the biosynthesis of heme.
por·phy·rin·o·gen (pôrf-rn-jn, -jn)
n.
Any of the intermediates in the biosynthesis of heme.

porphyrinogen
[por′f-rin′o-jen]
the reduced form of a porphyrin. The porphyrinogens are the functional intermediates in the biosynthesis of heme and if, oxidized to their corresponding porphyrins, such as occurs in porphyrias, are irreversibly removed from the biosynthetic pathway and accumulate in tissue. Their nomenclature corresponds to that of the porphyrins.

porphyrinogen [por″fĭ-rin´o-jen]
the reduced form of a porphyrin. The porphyrinogens are the functional intermediates in the biosynthesis of heme and if oxidized to their corresponding porphyrins, such as occurs in porphyrias, are irreversibly removed from the biosynthetic pathway and accumulate in tissues. Their nomenclature corresponds to that of the porphyrins.

porphyrinogen
partly reduced precursor form of porphyrin rings which can then have metals such as iron introduced to produce heme or other porphyrin structures.


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We were interested to find in this study that fecal coproporphyrin was a uniformly better diagnostic marker for VP than protoporphyrin, although the predominant porphyrinogen excreted in bile in individuals with VP is protoporphyrinogen (24).
For the ship-in-the-bottle synthesis, two preferred methods have been presented in the literature for the one-pot synthesis of meso-arylporphyrins: (i) the Adler method [22] that promotes the condensation of pyrrole with arylaldehydes in propionic acid followed by oxidation of the porphyrinogen with oxygen, and (ii) the nitrobenzene method [20] that promotes the condensation-oxidation of pyrrole with arylaldehydes in acetic acid/nitrobenzene, directly.
 
 
 
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