porphyrinogen

porphyrinogen

 [por″fĭ-rin´o-jen]
the reduced form of a porphyrin. The porphyrinogens are the functional intermediates in the biosynthesis of heme and if oxidized to their corresponding porphyrins, such as occurs in porphyrias, are irreversibly removed from the biosynthetic pathway and accumulate in tissues. Their nomenclature corresponds to that of the porphyrins.

porphyrinogen

/por·phy·rin·o·gen/ (por″fĭ-rin´o-jen) the reduced form of any porphyrin; they are the functional intermediates in the biosynthesis of heme.

porphyrinogen

[por′f-rin′o-jen]
the reduced form of a porphyrin. The porphyrinogens are the functional intermediates in the biosynthesis of heme and if, oxidized to their corresponding porphyrins, such as occurs in porphyrias, are irreversibly removed from the biosynthetic pathway and accumulate in tissue. Their nomenclature corresponds to that of the porphyrins.

porphyrinogen

partly reduced precursor form of porphyrin rings which can then have metals such as iron introduced to produce heme or other porphyrin structures.
References in periodicals archive ?
We were interested to find in this study that fecal coproporphyrin was a uniformly better diagnostic marker for VP than protoporphyrin, although the predominant porphyrinogen excreted in bile in individuals with VP is protoporphyrinogen (24).
Bile porphyrin and porphyrinogen levels in erythropoietic protoporphyria and variegate porphyria.
Porphyrinogens are the building blocks of all the hemoproteins, such as hemoglobin and the cytochrome enzymes.