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porphobilinogen

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.03 sec.
porphobilinogen /por·pho·bi·lin·o·gen/ (por″fo-bĭ-lin´ah-jin) an intermediary product in the biosynthesis of heme; it is produced in excess and excreted in the urine in acute intermittent porphyria.
por·pho·bi·lin·o·gen (pôrf-b-ln-jn, -jn)
n. Abbr. PBG
A porphyrin precursor found in large quantities in the urine in cases of acute or congenital porphyria.
porphobilinogen
[pôr′fōbilin′əjən]
a chromogen substance that is an intermediate in the biosynthesis of heme and porphyrins. It appears in the urine of people with porphyria, representing an error of metabolism. See also heme, porphyria.
porphobilinogen
an intermediary product in the biosynthesis of heme. Not detectable in normal animals.
porphobilinogen deaminase
an enzyme involved in the condensation of porphobilinogen. Now called uroporphyrinogen I synthetase.


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