Porotic hyperosotosis: relationship between orbital and vault lesions.
The causes of porotic hyperostosis and cribra orbitalia: a reappraisal of the iron-deficiency-anemia hypothesis.
The causes of porotic
hyperostosis and cribra orbita-lia: a reappraisal of the iron-deficiency-anemia hypothesis.
Another interesting finding in the thickened periosteum of one case (Case 2) was the presence of porotic
bone containing fat.
Angel's findings that sicklemia, thalassemia and favism (the G6PD deficiency) may protect a population to some extent against malaria, and their presence may be an indicator of the endemicity of malaria; but he does not find that the incidence of cases of porotic hyperostosis in skeletal remains is significant enough statistically to justify Angel's conclusion that malaria was virtually absent from the eastern Mediterranean region in the classical period (p.
19) But the aetiology of porotic hyperostosis is now seen as more complicated than when Angel and others wrote about the linkage between that condition and malaria.
total] Enamel 6/12 8/17 Hypoplasia Porotic
5/12 6/15 Hyperostosis Periostitis 0/5 0/9 Cerro Cerrillos: A1 A2 pathological [N.
The investigation focused on porous defects, broadly called porotic
hyperostosis, which were observed in the crania of the buried individuals, and the variations in this lesion were used to explore possible social differences.
Current diagnoses of porotic
hyperostosis with its remodeling of cranial bones in a sufferer with anaemia focus upon iron deficiency in the diet, although the phenotypic expression of abnormal haemoglobins should not be excluded from consideration, a subject that deserves more attention than covered here.
Some sections are particularly concise and elegant, for example, that on anaemia in the US southwest briskly summarizes current opinion on the various contributory factors in the aetiology of porotic
hyperostosis, with several examples of socio-economic interpretations.
Angel (1966; 1972: 97-8) suggested that much of the porotic
hyperostosis that he observed in EN human skeletal remains from Greece was due to thalassaemia that had 'developed as an evolutionary response to the newly spreading falciparum malaria', but the link between porotic
hyperostosis and malaria is not certain, nor is the date of its introduction to Greece (Borza 1995b; Grmek 1989; Laderman 1975).
hyperostosis in a marine-dependent California Indian population, American Journal of Physical Anthropology 69: 345-54.