porin


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porin

(pŏr′ĭn) [Gr. poros, passageway]
A channel-forming protein in cell membranes that facilitates the diffusion of water and small molecules in and out of the cell.

porin

a protein in the outer MEMBRANE of Gram-negative BACTERIA (see GRAM'S STAIN that allows the passage of small polar molecules across the membrane. The concentration gradient of each transported commodity is used to drive its movement through the membrane.
References in periodicals archive ?
Major organization : PORIN KAUPUNGIN HANKINTAPALVELUT
chromosomal AmpC cephalosporinase induction/derepression or porin modification) as the basis in Enterobacter species.
AVYCAZ also demonstrated in vitro activity against Pseudomonas aeruginosa in the presence of some AmpC beta-lactamases, and certain strains lacking outer membrane porin (OprD).
The small solution substances of molecules are able to pass this external membrane of bacteria through numerous porin proteins.
The mechanism of imipenem resistance involves the production of specific carbapenemases as well as the loss of porin proteins (Domenech-Sanchez et al.
VIM and IMP; (f) non-expression of porin genes and/or efflux pump-based antibiotic resistance (17).
Methods--We performed scanning electron microscopy (SEM) to determine structural and quantitative differences in biofilm produced by ackA (encoding acetate kinase), pta (encoding phosphotransacetylase), ackArcsB (encoding acetate kinase and regulator of capsule synthesis B), ackA-ompR (encoding acetate kinase and outer membrane porin regulator) and ackA-dcuR (encoding acetate kinase and regulator of (C4)-dicarboxylic acid megabolism) mutants, in comparison with their isogenic parent strain.
Vashist J, Rajeswari MR Structural investigations on novel porin, OmpAb from Acinetobacter baumannii.
With regard to antimicrobial agents, beta-lactams and quinolones must diffuse through porin channels in the outer membrane of the gram negative cell wall, but aminoglycosides and colistin interact with lipopolysaccharide on the outside of the outer membrane changing the permeability of the membrane so that they can pass through the membrane.
Functional MOMP probably serves as a porin, regulating the chlamydial developmental cycle by the passage of small molecules through the outer membrane (Stagg 1992).
Forsbacka arrives from his hometown club Porin Assat where he has spent the last five seasons playing in the famous SM Liiga in Finland, which is regarded as one of the top four leagues in the world.
Molecules, including iron, cross the mitochondrial outer membrane via a large diameter voltage-dependent anion channel called porin (37).