poorly differentiated

poorly differentiated

Oncology adjective Referring to a malignancy in which the malignant cells bear minimal resemblance to the cell from which they arose. Cf Well-differentiated.
References in periodicals archive ?
Intra- and postoperative pathology identified a poorly differentiated malignancy consistent with a melanoma.
Histomorphological examination by hematoxylin-eosin (H&E) stain (x400) revealed poorly differentiated tumour cell proliferation with large nucleoli and no melanin pigment (Fig.
Histology results demonstrated a poorly differentiated carcinoma with highly atypical cells, some of which were present in cohesive clusters, with others invading in a single file manner (Figure 1).
Because it is difficult to make a definitive diagnosis of a poorly differentiated carcinoma and other conditions of the thyroid on the basis of a fine needle aspiration sample alone, the volume presents images illustrating cytologic-histologic correlations, plus general issues to consider.
The NSCLCs are further classified into adenocarcinoma (ACA) (40%-50%), squamous cell carcinoma (SCC, 30%) and large cell carcinoma (9%), the latter being composed mostly of poorly differentiated ACA and a few uncommon cell types.
Papillary, follicular, Hurthle cell and poorly differentiated types of thyroid cancer are classified as "differentiated thyroid cancer" and account for approximately 94 percent of all thyroid cancers.
The expression and distribution of the Orexin receptor was more widespread in Group 1 than in the other groups and was higher in patients with poorly differentiated malignancy.
21%, respectively) and poorly differentiated (28% vs.
The occurrence of these tumours in the head and neck is rare (6,7) and we report the fine needle aspiration [FNA] cytology of a PNET arising in the posterior tongue, that had metastasized to cervical lymph nodes in a 47 year old woman, initially mistaken for a poorly differentiated non-keratinizing squamous cell carcinoma.
In gel cultures CCE spheres grew aggressively and formed more intricate structures than control spheres; microscopically, these structures appeared malignant, with poorly differentiated cells of many shapes and sizes.
These tumors are often poorly differentiated or undifferentiated and may have atypical presentation.
An adjacent peribronchial lymph node was positive for tumour (pN1), however due to the poorly differentiated morphology of the tumour cells it was unclear as to which tumour it originated.