polyposis coli


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polyposis coli

Etymology: Gk, polys, many, pous, foot, osis, condition, kolikos colon
a condition of multiple polyps in the large intestine.

polyposis coli

Polyposis of the large intestine.
See also: polyposis

polyposis coli

A rare, inherited disorder of the colon in which between 100 and 1000 polyps occur on the lining of the colon and rectum. Cancerous change in some of these is almost inevitable by the age of 40 and it is usual to remove the colon, and sometimes the rectum, to prevent this.
References in periodicals archive ?
Desmoid tumour biology in patients with familial adenomatous polyposis coli.
Identification and characterization of the familial adenomatous polyposis coli gene.
Hyperplastic polyposis coli syndrome and colorectal carcinoma.
To confirm effects on Wnt signaling, analysis of tumor tissues from 5% BB-fed mice revealed lower -catenin expression and glycogen synthase kinase-3 phosphorylation with greater expression of the-catenin inhibitory protein adenomatous polyposis coli compared to controls.
That gene, adenomatous polyposis coli (APC) and its downstream signaling molecules, are mutated or deficient in 80 percent of all human colon cancers, Wu pointed out.
Using Indivumed's highly standardized biobank, the researchers found elevated levels of mutated adenomatous polyposis coli (APC) gene in the plasma of patients with advanced stage colorectal cancers.
The paradigm of heritable CRC is familial adenomatous polyposis coli (APC), in which mutations of the APC gene on chromosome arm 5q cause the development of many of the polyps found in patients under the age of 30.
In an attempt to develop a single gene-based test that would help detect clinically significant, but premetastatic colorectal tumors, researchers at Johns Hopkins University, Baltimore, turned to the adenomatous polyposis coli (APC) gene.
Four of Patricia's five sisters inherited the tragic genetic legacy of familial polyposis coli which can lead to colon cancer.
Analyzing fecal DNA for mutations of adenomatous polyposis coli (APC) gene can identify early cases of colorectal cancer, according to a report in the Jan.
Attentuated Adenomatous Polyposis Coli (AAPC) is a variant of FAP caused by a mutation in the APC gene and inherited in the same way as classical FAR.
The screening test of choice is an adenomatous polyposis coli (APC) gene test, which should be done at age 10-12 years, following formal pretest genetic counseling and informed consent of both patient and parents.