polyposis coli


Also found in: Dictionary.
Related to polyposis coli: Familial adenomatous polyposis, Familial Polyposis Coli

polyposis coli

Etymology: Gk, polys, many, pous, foot, osis, condition, kolikos colon
a condition of multiple polyps in the large intestine.

polyposis coli

Polyposis of the large intestine.
See also: polyposis

polyposis coli

A rare, inherited disorder of the colon in which between 100 and 1000 polyps occur on the lining of the colon and rectum. Cancerous change in some of these is almost inevitable by the age of 40 and it is usual to remove the colon, and sometimes the rectum, to prevent this.
References in periodicals archive ?
Attentuated Adenomatous Polyposis Coli (AAPC) is a variant of FAP caused by a mutation in the APC gene and inherited in the same way as classical FAR.
The screening test of choice is an adenomatous polyposis coli (APC) gene test, which should be done at age 10-12 years, following formal pretest genetic counseling and informed consent of both patient and parents.
The company is seeking marketing approval of Aptosyn(TM) (exisulind) for the treatment of familial adenomatous polyposis ("FAP"; also known as adenomatous polyposis coli, or "APC"), a rare disease that puts those afflicted at high risk of developing colon cancer.
With the exception of presymptomatic testing for familial polyposis coli [a genetic disorder resulting in colon cancer], there is no documented benefit to the child of testing for cystic fibrosis carrier status or presymptomatic testing for Huntington's disease.
HR15 Colonoscopy: Persons with a family history of familial polyposis coli or cancer family syndrome, a) two or more first degree relatives with colon cancer, start colonoscopy at age 35 or 5 yrs less than youngest relative with cancer and continue every 3-5 years.
com/research/pfmdk2/familial) has announced the addition of Global Markets Direct's new report "Familial Adenomatous Polyposis Coli - Pipeline Review, H2 2012" to their offering.
Giardiello and his associates tested sulindac as primary chemoprevention in 41 people who carried the inherited germ-line mutation of the adenomatous polyposis coli (APC) gene located at chromosome 5q21 but who were phenotypically normal.
anticipates a delay in the filing of its NDA for its novel investigational drug, PREVATAC(tm) (exisulind) for Adenomatous Polyposis Coli (APC), which was initially planned for March of this year.
17 NATURE that roughly 60 percent of each group of patients had a mutation in the adenomatous polyposis coli (APC) gene, known to cause an inherited predisposition to cancer-prone colorectal polyps.
com/research/4d5qcz/familial_adenomato) has announced the addition of Global Markets Direct's new report "Familial Adenomatous Polyposis Coli - Pipeline Review, H1 2012" to their offering.
Classic familial adenomatous polyposis (FAP) (6) is an autosomal dominant inherited disease caused by germline mutations in the adenomatosis polyposis coli (APC) (7) tumor suppressor gene.
The mission of the HCCA is the prevention of colon cancer caused by the inherited syndromes of colon cancer including: Familial Adenomatous Polyposis (FAP), Gardner syndrome, Juvenile Familial Polyposis, Hereditary Non Polyposis Colorectal Cancer (HNPCC), Attenuated Adenomatous Polyposis Coli (AAPC) and Peutz-Jeghers Syndrome.