polypill


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polypill

A popular term for a drug that combines multiple active pharmaceutical ingredients into a single pill.

polypill

[″ + L. pilula, a small mass]
1. A pill that contains a mixture of health-promoting ingredients.
2. A panacea.

polypill

A proposed medication, to be taken daily, consisting of a STATIN drug to lower blood cholesterol, small doses of three drugs to control blood pressure, 0.8 mg of folic acid to reduce blood homocysteine, and 70 mg of aspirin to reduce the clotting tendency of the blood. The principal targets of this combination are heart attacks and strokes, and the proposers estimate that people who take the polypill will have reduced their risk of these disasters by 80 per cent and will enjoy substantially prolonged lives. The idea has aroused much controversy.
References in periodicals archive ?
Professor Valentin Fuster, General Director of CNIC, Madrid, and Director of Mount Sinai Heart, New York and leader of the CNIC-Ferrer polypill project, opened the presentation and highlighted the clinical challenges presented by secondary cardiovascular risks.
The researchers are confident that combining several drugs in one pill will encourage medication to be taken more reliably, but despite also being cheaper, the polypill remains unlicensed in Britain because aspirin can cause gastric bleeding.
Because mailed education and disease management could be more effective in patients who were prescribed multiple cardiovascular drugs than those who were prescribed a single drug, we conservatively assumed that the effectiveness of each intervention was 50 percent of the base-case estimate when combined with polypill use.
The polypill is a layered tablet containing three blood pressure-lowering drugs and a cholesterol-lowering statin.
A group of 84 men and women aged 50 and over were randomly given the polypill or an inactive "dummy" tablet for a period of three months.
The polypill does away with this confusion and so it's hoped it will improve compliance and help prevent people stopping their medication or taking it incorrectly.
Cardiovascular complications of HIV: an overview of risk and a novel approach to prevention-the HIV polypill study.
The principle of the polypill is simple--put 5 drugs known to reduce cardiovascular risk into a single pill and give it to middle-aged people to prevent cardiovascular disease.
The polypill will eventually come in my view, but it will be some time before the Food and Drug Administration approves a single pill containing five or six drugs to treat two or more conditions.
Based on the reduction in risk factors seen in the trial, Yusuf projected the polypill could reduce heart disease by 60% and stroke by 50%.
Scientists compared Polycap, a five-drug polypill, with combinations of its different components to assess effectiveness and safety.