polypill


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polypill

A popular term for a drug that combines multiple active pharmaceutical ingredients into a single pill.

polypill

[″ + L. pilula, a small mass]
1. A pill that contains a mixture of health-promoting ingredients.
2. A panacea.

polypill

A proposed medication, to be taken daily, consisting of a STATIN drug to lower blood cholesterol, small doses of three drugs to control blood pressure, 0.8 mg of folic acid to reduce blood homocysteine, and 70 mg of aspirin to reduce the clotting tendency of the blood. The principal targets of this combination are heart attacks and strokes, and the proposers estimate that people who take the polypill will have reduced their risk of these disasters by 80 per cent and will enjoy substantially prolonged lives. The idea has aroused much controversy.
References in periodicals archive ?
The initial concept of the polypill was greeted with considerable skepticism by the medical community which has viewed attacking cardiovascular mortality as a one-on-one experience between patient and physician.
The original concept of the polypill was to give it to everyone over age 55.
The researchers are confident that combining several drugs in one pill will encourage medication to be taken more reliably, but despite also being cheaper, the polypill remains unlicensed in Britain because aspirin can cause gastric bleeding.
Because mailed education and disease management could be more effective in patients who were prescribed multiple cardiovascular drugs than those who were prescribed a single drug, we conservatively assumed that the effectiveness of each intervention was 50 percent of the base-case estimate when combined with polypill use.
Experts called for the polypill to be made generally available to the UK population "without delay".
Experts last night called for the polypill to be made generally available to the UK population "without delay".
If people took the polypill from age 50, an estimated 28 per cent would benefit by avoiding or delaying a heart attack or stroke.
Polypharmacy, more than one drug in a single pill, has come of age with the new polypill, the three-in-one tablet for treating high blood pressure.
The polypill holds promise for the treatment of chronic disease.
For years researchers around the world have explored the concept of a polypill that combined medications to help manage hypertension, high cholesterol and to help thin the blood for patients at a higher risk of clotting.
These authors developed the concept which claimed that a polypill comprising six components and administered to each individual older than 55 years would reduce the incidence of cardiovascular disease by more than 80%.