HyperChem provides databases containing residues for constructing proteins, polynucleotides
, either as isolated molecules or within a water environment.
The enzyme, called human polynucleotide
phosphorylase or hPNPaseold-35, drives cancerous cells to irreversibly lose their growth potential and acquire properties of more normal cells, a process called terminal cell differentiation.
8,323,884 and 8,313,899 "Isolated SNARE YKT6 Genomic Polynucleotide
Fragments from Chromosome 7 and their Uses" claim an isolated nucleic acid molecule that encodes a polypeptide which has SNARE YKT6 activity and is one of the highly conserved from yeast to human molecules.
University of California (Oakland, CA) has patented an isolated polynucleotide
sequence encoding a chimeric CD154, comprising a first nucleotide sequence encoding an extracellular subdomain of non-human CD154, preferably murine CD154, that replaces a cleavage site of human CD154, and a second nucleotide sequence encoding an extracellular subdomain of human CD154 that binds to a human CD154 receptor.
Oxford Gene Technology filed law suits in the US and UK alleging that Affymetrix has infringed on two of its patents involving analysis of polynucleotide
8,192,930, entitled "Method for Sequencing a Polynucleotide
Oxford Gene Technology filed suit against Affymetrix in the US District Court in Delaware, alleging that Affymetrix's GeneChip product line infringes its patent, "Apparatus and Method for analyzing polynucleotide
sequences and (a) method of generating olignucleotide arrays.
6,514,699 entitled "Multiplex Polynucleotide
Capture Methods and Compositions.
A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide
7,754,424, titled "Isolated genomic polynucleotide
fragments from chromosome 12 that encode human carboxypeptidase M and the human mouse double minute 2 homolog," claims isolated genomic polynucleotide
fragments that encode human mouse double minute 2 homolog as well as fragments of contiguous exon-intron and intron-exon regions, transcription factor binding regions and other noncoding regions such as 5' and 3' noncoding regions and intron regions, complementary polynucleotides
, microarrays, vectors and host cells containing these fragments.
Cyto Pulse technology is used in a wide range of fields including monoclonal antibody discovery, polynucleotide
vaccine production, and delivery of polynucleotide
Ryogen LLC, a genomic start-up company, has been awarded a new patent titled "Isolated Genomic Polynucleotide
Fragments from Chromosome 7".