polyneuropathy


Also found in: Dictionary, Thesaurus, Financial, Encyclopedia, Wikipedia.

polyneuropathy

 [pol″e-noo͡-rop´ah-the]
a disease involving several nerves.
amyloid polyneuropathy polyneuropathy caused by amyloidosis; symptoms may include dysfunction of the autonomic nervous system, carpal tunnel syndrome, and sensory disturbances in the extremities.
familial amyloid polyneuropathy autosomal dominant amyloid polyneuropathy occurring in hereditary amyloidosis; subtypes include Finnish type, Indiana type, Iowa type, and Portuguese type. The Finnish and Indiana types are slowly progressive, whereas in the Portuguese and Iowa types death may occur within 7 to 10 years.
erythredema polyneuropathy acrodynia.

pol·y·neu·rop·a·thy

(pol'ē-nū-rop'ă-thē),
1. A disease process involving a number of peripheral nerves (literal sense).
2. A nontraumatic generalized disorder of peripheral nerves, affecting the distal fibers most severely, with proximal shading (for example, the feet are affected sooner or more severely than the hands), and typically symmetrically; most often affects motor and sensory fibers almost equally, but can involve either one, either solely or very disproportionately; classified as axon degenerating (axonal), or demyelinating; many causes, particularly metabolic and toxic; familial or sporadic. Synonym(s): polyneuritis
[poly- + G. neuron, nerve, + pathos, disease]

polyneuropathy

/poly·neu·rop·a·thy/ (-ndbobr-rop´ah-the) neuropathy of several peripheral nerves simultaneously.
amyloid polyneuropathy  polyneuropathy associated with amyloidosis, of either the primary or the familial type; symptoms may include dysfunction of the autonomic nervous system, carpal tunnel syndrome, and sensory disturbances in the limbs.
erythredema polyneuropathy  acrodynia.
familial amyloid polyneuropathy  autosomal dominant amyloid polyneuropathy, associated with familial amyloidosis and most commonly involving a mutant form of the protein transthyretin.; it may be subclassified on the basis of affected kinships or on the basis of symptoms and the biochemical composition of the affected fibrils.

polyneuropathy

(pŏl′ē-no͝o-rŏp′ə-thē)
n.
Neuropathy involving several peripheral nerves.

polyneuropathy

[-noo͡rop′əthē]
Etymology: Gk, polys, many, neuron, nerve, pathos, disease
a condition in which many peripheral nerves are afflicted with a disorder.

polyneuropathy

Chronic inflammatory polyneuropathy, critical illness polyneuropathy, familial amyloidotic polyneuropathy, multiple neuropathy, peripheral neuropathy, polyneuritis, sensorimotor polyneuropathy Neurology The simultaneous inflammation of the motor and/or sensory components of 2 or more peripheral nerves. See Mononeuropathy.

pol·y·neu·rop·a·thy

(pol'ē-nūr-op'ă-thē)
1. A disease process involving a number of peripheral nerves (literal sense).
2. A nontraumatic generalized disorder of peripheral nerves, affecting the distal fibers most severely, with proximal shading (e.g., the feet are affected sooner or more severely than the hands), and typically symmetrically; most often affects motor and sensory fibers almost equally, but can involve either one solely or very disproportionately; classified as axon degenerating (axonal) or demyelinating; many causes, particularly metabolic and toxic; familial or sporadic in nature.
Synonym(s): polyneuritis.
3. Synonym(s): acrodynia (2) . Synonym(s): multiple neuritis.
[poly- + G. neuron, nerve, + pathos, disease]

polyneuropathy

generalized autonomic, sensory and motor neuropathy; characteristic of late-stage diabetes mellitus

pol·y·neu·rop·a·thy

(pol'ē-nūr-op'ă-thē)
1. Disease process involving several peripheral nerves (literal sense).
2. Nontraumatic generalized disorder of peripheral nerves, affecting distal fibers most severely, with proximal shading.
[poly- + G. neuron, nerve, + pathos, disease]

polyneuropathy

a disease involving several nerves. See also neuropathy.

acute idiopathic polyneuropathy
see idiopathic polyradiculoneuritis.
distal polyneuropathy of Birman cats
a noninflammatory, diffuse loss of myelinated fibers in the distal portions of the central and peripheral nervous systems, resulting in progressive hindlimb ataxia and hypermetria in young Birman kittens. Believed to be inherited as an autosomal recessive trait.
familial polyneuropathy
see Boxer progressive axonopathy, hereditary neuronal abiotrophy of Swedish Lapland dogs, giant axonal neuropathy.
hypoglycemic polyneuropathy
associated with hyperinsulinism of β-cell insulinomas; there is generalized muscle weakness, paraparesis and tetraparesis.
hypothyroid polyneuropathy
a progressive lower motor neuron disease associated with hypothyroidism.
idiopathic polyneuropathy
see idiopathic polyradiculoneuritis.
immune-mediated polyneuropathy
may occur in association with systemic lupus erythematosus in dogs.
References in periodicals archive ?
Brown WF, Feasby TE: Sensory evoked potentials in Guillain-Barre polyneuropathy.
Our patient was diagnosed with anti-MDA5-mediated demyelinating polyneuropathy and dermatomyositis based on her clinical presentation, neurological examination results, and the presence of serum anti-MDA5.
AIP should be kept in mind in cases presenting with motor polyneuropathy even if the diagnosis was not done previously, AIP has various systemic findings that can lead to the diagnosis, and anti-SSA positivity might be seen in AIP, which is not wellknown among neurologists (10).
Our study concludes that hypothyroid individuals are more predisposed to develop sensory motor axonal polyneuropathy.
Abylaiuly Z, Strokov I, 2009, Treatment of symptomatic polyneuropathy with actovegin in type 2 diabetic patients.
Nerve histopathology of the different forms of FAP is similar showing fiber-length-dependent polyneuropathy, loss of myelinated nerves, particularly small myelinated and unmyelinated nerve fibers.
The report reviews key players involved in the therapeutics development for Familial Amyloid Polyneuropathy (Transthyretin Amyloidosis, Corino de Andrade's Disease) and enlists all their major and minor projects
Sensory ataxia and progressive sensory polyneuropathy were observed in one patient (No.
Variable presentations of TTR-related familial amyloid polyneuropathy in seventeen patients.
This report provides comprehensive information on the therapeutic development for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
The most common diagnosis was carpal tunnel syndrome in 721(17%) patients, followed by polyneuropathy 312(7.
Recently, a case of sacroiliitis and polyneuropathy was reported.