polymorphous low-grade adenocarcinoma


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

polymorphous low-grade adenocarcinoma

A low-grade carcinoma of older patients that affects minor salivary glands, especially the palate (where 60% of PLGAs occur), far less often than major salivary and nasopharyngeal glands.

Management
Excision, post-operative radiation therapy.

Prognosis
Good; recurrence, 12%; local extension, 10%.
References in periodicals archive ?
Pulmonary metastasis of polymorphous low-grade adenocarcinoma of the minor salivary gland.
C-kit expression distinguishes salivary gland adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma.
C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma.
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm that almost always arises in the minor salivary glands.
The following year, Evans and Batsakis used the term polymorphous low-grade adenocarcinoma to describe this malignancy as a clinically and pathologically discrete entity.
3) The neoplastic cells in polymorphous low-grade adenocarcinoma grow in a combination of two or more of these five basic architectural patterns: (1) tubules and ductlike structures, (2) cords and trabeculae, (3) solid nests, (4) cribriform pattern with pseudoluminal spaces, and (5) papillae.