polymorphonuclear leukocyte

polymorphonuclear leukocyte

n. Abbr. PMN

A white blood cell, usually neutrophilic, having a nucleus that is divided into lobes connected by strands of chromatin. Also called multinuclear leukocyte.

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polymorphonuclear leukocyte,

a white blood cell containing a segmented lobular nucleus; an eosinophil, basophil, or neutrophil. See also granulocyte.

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leukocyte (lōō´kōsīt),

n a white blood cell circulating in the blood. See also lymphocyte and monocyte.

leukocyte, basophilic (basophil),

n a type that has coarse granules stainable with basic dyes and a bent lobed nucleus.

leukocyte count,

n the number of white blood cells in a cubic millimeter of blood. Normal values range from 5000 to 10,000/mm³.

leukocyte, eosinophilic (eosinophil),

n a type that has coarse granules stainable with eosin and a bilobed nucleus.

leukocyte, immature,

n a form of white blood cell usually found in disease (e.g., myelocytes, myeloblasts, lymphoblasts).

leukocyte, monocyte,

n an agranulocyte white blood cell.

leukocyte, polymorphonuclear (PMN), (neutrophil),

n 1. a type with finely granular cytoplasm, an irregularly lobulated nucleus, and the appearance of a microphage. It is found in the tissues during acute inflammatory processes and in the superficial surface aspects of a lesion during subacute or chronic inflammation. It is the predominating leukocyte of the blood. Blood levels may be increased during acute inflammatory states and myelogenous leukemia, and decreased in agranulocytosis. See also neutropenia; polymorphonuclear leukocyte; neutrophilia.

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leukocyte

a white blood cell capable of ameboid movement, whose chief function is to protect the body against microorganisms causing disease and which comprise: granulocytes (basophils, eosinophils, neutrophils), nongranulocytes (lymphocytes, monocytes) and thrombocytes (platelets).

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bovine leukocyte adhesion deficiency

lethal hematological defect inherited as a recessive trait in Holstein cattle; characterized by poor growth, recurrent infection and poor responsivity to standard treatments in calves from 2 to 8 weeks of age. Profound neutrophilia. Death supervenes before two years of age. Called also BLAD.

canine leukocyte adhesion deficiency

an autosomal recessive disease in Irish setters. Neutrophils lack CD11/CD18 adhesion proteins. Affected dogs have a marked neutrophilia and recurrent bacterial infections from an early age.

leukocyte count

tabulation of the numbers and kinds of leukocytes in a blood sample.

endothelial leukocyte

see endotheliocyte.

leukocyte functional antigens

a group of cell surface antigens involved in intracellular adhesion.

granular l's

granulocytes; leukocytes containing abundant granules (lysosomes) in their cytoplasm, including neutrophils, eosinophils and basophils.

leukocyte migration-inhibition factor

a lymphokine elaborated by activated T or B lymphocytes that inhibits polymorphonuclear leukocyte migration.

polymorphonuclear leukocyte

any of the fully developed, segmented cells of the granulocyte series, especially a neutrophil, whose nuclei contain three or more lobes joined by filamentous connections.