polymerase


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Related to polymerase: RNA polymerase, Taq polymerase

polymerase

 [pah-lim´er-ās]
an enzyme that catalyzes polymerization.
polymerase chain reaction a rapid technique for in vitro amplification of specific DNA or RNA sequences, allowing small quantities of short sequences to be analyzed without cloning.

pol·ym·er·ase

(pol-im'ĕr-ās),
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

/po·lym·er·ase/ (pah-lim´er-ās) an enzyme that catalyzes polymerization.

polymerase

(pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
n.
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.

polymerase

[pə·lim′ər·ās]
any enzyme that catalyzes polymerization, especially of nucleotides to polynucleotides.

POLA1

A gene on chromosome Xp22.1-p21.3 that encodes the catalytic subunit of DNA polymerase that plays a key role in initiating DNA replication.

pol·ym·er·ase

(pŏ-lim'ĕr-ās)
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

Any enzyme that promotes the linkage of a number of similar or identical chemical subunits into repetitive long-chain molecules (polymers), especially of NUCLEOTIDES to form DNA or RNA. Derivation as in POLYMER with the -ase suffix denoting an enzyme.

polymerase

an enzyme that catalyses the joining of DNA or RNA nucleotides.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
Thus, if tested DNA polymerase is incapable to use some of modified nucleotides as a substrate, the formation of full 40 nucleotide duplex does not occur, which significantly facilitates the visualization of the results of PCR.
The effect of polymerase and primer concentrations in PCR with < 1-s cycles was studied by use of a 49-bp fragment of IL10RB (interleukin-10 receptor, [beta]), shown as both 2-dimensional (Fig.
Previous studies have shown that PB1-F2 of the A/WSN/33 strain (WSN;H1N1) upregulates viral polymerase activity in vitro [11].
This makes the nascent strand ssDNA, allowing the opposing primer (Primer l in Figure 2c) to anneal, and DNA polymerase to again start strand synthesis.
The unusual origin of the polymerase chain reaction.
says, "If you understand the structure and the mechanism of how RNA polymerase works, it will help yon understand gene regulation," which in turn is "hugely important" to studies of disease.
This is a surprising suggestion, because it is thought that TLS polymerases are inaccurate and that they form mispairs that increase the mutation rate.
Comparison of Virapap filter hybridization with polymerase chain reaction and Southern blot hybridization methods for detection of human papillomavirus in tonsillar and pharyngeal cancers.
Other methods have been used to measure polymerase kinetics, including atomic force microscopy (1), light microscopy (2), single molecule optical trapping (3), quench flow (4), stopped flow (4-7), and quartz crystal microbalance (8).
Substrate modified by DNA polymerase serves as a target for a quantitative polymerase chain reaction (qPCR).
3 October 2013 - US sequencing platform developer Pacific Biosciences of California Inc (NASDAQ:PACB) said Thursday it had introduced a new P5 polymerase and C3 chemistry combination (P5-C3) to be used in complex genome projects.

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