polymerase


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to polymerase: RNA polymerase, Taq polymerase

polymerase

 [pah-lim´er-ās]
an enzyme that catalyzes polymerization.
polymerase chain reaction a rapid technique for in vitro amplification of specific DNA or RNA sequences, allowing small quantities of short sequences to be analyzed without cloning.

pol·ym·er·ase

(pol-im'ĕr-ās),
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

/po·lym·er·ase/ (pah-lim´er-ās) an enzyme that catalyzes polymerization.

polymerase

(pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
n.
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.

polymerase

[pə·lim′ər·ās]
any enzyme that catalyzes polymerization, especially of nucleotides to polynucleotides.

POLA1

A gene on chromosome Xp22.1-p21.3 that encodes the catalytic subunit of DNA polymerase that plays a key role in initiating DNA replication.

pol·ym·er·ase

(pŏ-lim'ĕr-ās)
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

Any enzyme that promotes the linkage of a number of similar or identical chemical subunits into repetitive long-chain molecules (polymers), especially of NUCLEOTIDES to form DNA or RNA. Derivation as in POLYMER with the -ase suffix denoting an enzyme.

polymerase

an enzyme that catalyses the joining of DNA or RNA nucleotides.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
Working out the structure of RNA polymerase was "a marvelous achievement," says James T.
This activity was previously demonstrated in polymerase beta, which is active in a repair pathway called base excision repair (BER).
Diagnostic sensitivity of polymerase chain reaction and Southern blot hybridization for the detection of human papillomavirus DNA in biopsy specimens from cervical lesions.
The 155 page, August 2011 publication studies the global polymerase chain reaction technology market for the period 2010-2015, providing in-depth analysis of the market, the participants, their products/techniques and the opportunities it presents.
This "sample" is then lysed in the presence of the ETGA reaction components and then incubated for a brief period to allow DNA extension to occur if DNA polymerase is present.
The polymerase then attaches this cap to its own mRNA.
Tokyo, Japan, July 26, 2005 - (JCNN) - Takara Bio announced on July 25 that it has launched PrimeSTAR HS DNA Polymerase, a polymerase chain reaction (PCR) enzyme with high fidelity and increased DNA amplification efficiency.
Rockefeller University (New York, NY) has patented an isolated DNA molecule from a thermophilic bacterium which encodes a DNA polymerase III-type enzyme subunit.
Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair.
Our examination of footplate fragments by reverse transcription polymerase chain reaction testing in 95 patients with otosclerosis revealed the presence of measles virus RNA in 83% of cases.
A principal component of the mtDNA replisome is the mtDNA polymerase [gamma].
A STUDY OF THE SAFETY AND PHARMACOKINETICS OF SINGLE ASCENDING ORAL DOSES OF INX-08189, A NUCLEOTIDE POLYMERASE INHIBITOR, IN HEALTHY SUBJECTS"

Full browser ?