At present, glucose, polyglucose, and amino acids are being used in commercial PDFs.
market (Extraneal, Baxter Healthcare, McGaw Park, Illinois) contains polyglucose 25%, sodium 133 mEq/L, calcium 1.
The absorption of polyglucose has been reported to be 14.
The MIDAS Study revealed that after one month of polyglucose treatment, elevated steady state levels of oligosaccharides were maintained (Mistry et al.
Iso-osmolar polyglucose solutions achieve peritoneal UF by colloid osmosis allowing net UF during long dwell exchanges due to its slow absorption.
The use of commercially available polyglucose solutions has been associated with various side effects and manufacturing problems.
Recurrent culture negative peritonitis associated with exposure to polyglucose PDF has been well documented (Pinerolo, Porri, & D'Amico, 1999; Goffin & Scheiff, 2002; Williams & Foggensteiner, 2002; Reichel, Schulze, Dietze, & Mende, 2001; Jenkins, Leng, Shortland, Brown, & Wilkie, 2001; Montagnac, Slingeneyer, & Schillinger, 2001; Del Rosso, Di Liberato, Perilli, Cappelli, & Bonomini, 2000; Heeling, Brause, Plum, & Grabensee, 2001; Bassi & Dagostina, 2002; Boer, Vos, & Fieren, 2003; Basile, Padova, Montanaro, & Giordano, 2003).