polyglandular autoimmune syndromes

polyglandular autoimmune syndromes

a group of disorders manifested by subnormal functioning of more than one endocrine gland. Type I is characterized by the appearance of mucocutaneous candidiasis, often occurring in childhood, and is associated with hypoparathyroidism and adrenal insufficiency. It occurs in siblings, without involvement of other generations in the family. Type II involves primary adrenal insufficiency and primary thyroid failure occurring in the same patient for unclear reasons. Many of these patients have an autoimmune disorder and form antibodies against cellular fractions of many endocrine glands. Type II is also called Schmidt's syndrome. Also called polyendocrine deficiency syndromes, polyglandular autoimmune diseases.

Patient discussion about polyglandular autoimmune syndromes

Q. My boy has diabetes. Recently he was diagnosed with vitiligo. What is it and what can be the reason for this? My boy has diabetes. recently he was diagnosed with vitiligo. Our doctor said that he hopes it not a polyglandular autoimmune syndrome. what is vitiligo and what does this big phrase (polyglandular autoimmune syndrome) mean?

A. Vitiligo is a pigmentation disorder and the major cause of vitiligo is the autoimmunity. Some internal factor cause the destruction of melanocytes cell which produce the melanin a substance responsible for the coloration of skin. this lack of melanin infect results in <a href="http://www.antivitiligo.com/">white patch on skin</a> of hypo pigmentation.
Normally vitiligo is not related with other disease like diabetes. However a little inheritance may include in the occurence of vitiligo.

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References in periodicals archive ?
Vitiligo associated with other autoimmune diseases: polyglandular autoimmune syndrome types 3B + C and 4.