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polyglandular

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polyglandular /poly·glan·du·lar/ (-glan´du-lar) pluriglandular.
pol·y·glan·du·lar (pl-glnj-lr)
adj.
Pluriglandular.

pluriglandular [ploor″ĭ-glan´du-ler]
pertaining to several glands or their secretions.

polyglandular
pertaining to or affecting several glands.

polyglandular syndrome
immune-mediated disease of more than one organ or endocrine gland in the animal, associated with the presence of autoantibodies. A heritable disorder in humans. In dogs, hypothyroidism and hypoadrenocorticism (Addison's disease) are the most frequent findings. Called also Schmidt's syndrome.

Patient discussion about polyglandular.

Q. My boy has diabetes. Recently he was diagnosed with vitiligo. What is it and what can be the reason for this? My boy has diabetes. recently he was diagnosed with vitiligo. Our doctor said that he hopes it not a polyglandular autoimmune syndrome. what is vitiligo and what does this big phrase (polyglandular autoimmune syndrome) mean?

A. Vitiligo is a pigmentation disorder and the major cause of vitiligo is the autoimmunity. Some internal factor cause the destruction of melanocytes cell which produce the melanin a substance responsible for the coloration of skin. this lack of melanin infect results in <a href="http://www.antivitiligo.com/">white patch on skin</a> of hypo pigmentation.
Normally vitiligo is not related with other disease like diabetes. However a little inheritance may include in the occurence of vitiligo.

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Key Words: autoimmune thyroid disease, Graves disease, celiac disease, hypoparathyroidism, autoimmune polyglandular syndromes ********** Graves disease, celiac disease and idiopathic hypoparathyroidism are all thought be autoimmune in pathogenesis.
As many as 40% of patients with idiopathic Addison's disease may exhibit polyglandular endocrine syndromes in which immunologic tissue injuries occur in the thyroid, parathyroid, ovary, pancreas, and skin.
11) In a subsequent study, 56% of patients with acquired hypoparathyroidism and autoimmune polyglandular syndrome 1 had autoantibodies directed against the extracellular portion of the parathyroid calcium-sensing receptor (CaSR), the autoantigen now suggested to cause parathyroid failure.
 
 
 
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