In a paper published in 2014 in the journal Nature Chemistry, Burke showed that most of the motifs of a class of compounds called polyenes
could be made from just 12 basic building blocks by repeating a simple chemical reaction.
Among all the drugs for liver disease, polyene
phosphatidyl choline is the natural diglyceride of cholinephosphoric acid and unsaturated fatty acids which can protect hepatocyte from lesion, alleviate inflammation reaction and improve the detoxification of the liver.
Transport through liquid membrance bilayers generated by lecithin, cholesterol and lecithin-cholesterol mixtures-studies in the presence of polyene
Development of resistance to polyene
antibiotics in Candida albicans.
5) Amphotericin is a polyene
macrolide that binds preferentially to ergosterol in the fungal cell membrane; it also binds human cholesterol.
Alternative treatments for visceral Leishmanisis include the polyene
antibiotic amphotericin B that has highly effective less toxic lipid formulations (Sundar 2003).
Key statement: A crosslinkable and crosslinked organosilicon polymer which is prepared from a mixture of a reactive polysiloxane resin having both reactive carbon-carbon double bonds and silicone-hydrogen groups, characterized by alternating structures of polycyclic polyene
residue and cyclic (or tetrahedral) polysiloxane residue, and either vinyl terminated fluorine-containing polysiloxane or vinyl terminated phenyl-substituted siloxane.
The alternative double bonds and conjugation in the polyene
compounds are one of the main properties in these compounds.
The active medium consists of diarylalkene derivatives, triene derivatives, or polyene
Structure of fatty acids and lipids: Introduction; Fatty-acid nomenclature; Fatty acids--main structural features; Saturated acids; Monoene acids; Methylene-interrupted polyene
acids; Other unsaturated acids; Branched chain and cyclic acids; Oxygenated acids; Halogenated fatty acids; Introduction to lipid structure; Acylglycerols; Wax esters; Glycosyldiacylglycerols; Phospholipids; Ether lipids; Sphingolipids.
Additionally, Congo red, anthracyclines, dimethyl sulfoxide, glycerol, and polyene
antibiotics have some degree of activity in vitro or in experimental animals (6).
Studies that have included antifungal susceptibility testing have demonstrated that B capitatus is usually sensitive to the polyene
amphotericin B (minimum inhibitory concentration [MIC], 0.