polycythemia rubra vera
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a chronic form of polycythemia of unknown cause; characterized by bone marrow hyperplasia, an increase in blood volume as well as in the number of red blood cells, redness or cyanosis of the skin, and splenomegaly.
polycythemia rubra vera (PV)
Etymology: Gk, polys, many, kytos, cell, haima, blood, L, ruber, red, verus, true
a myeloproliferative neoplasm characterized by an elevated red blood cell count and mass, hematocrit, hemoglobin, leukocytes, and thrombocytosis. The skin and mucous membranes acquire a maroon or plum color, and hepatomegaly, splenomegaly, hypertension, and neurological symptoms develop. The condition is associated with the JAK2 mutation. Also called primary polycythemia.