polycystic ovarian disease

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polycystic ovarian disease

Polycystic ovaries, sclerocystic ovary disease, Stein-Leventhal syndrome Gynecology An idiopathic condition affecting 3.5-7.0% of ♀, and most common cause of familial hirsutism Clinical Obesity, hirsutism, galactorrhea, 2º amenorrhea following dysmenorrhea, acne vulgaris, and an ↑ risk of endometrial carcinoma due to unopposed estrogenic stimulation; PCO may be associated with CNS trauma or injury in childhood Diagnosis Palpation, ultrasonography Lab ↑ LH or LH/FSH ratio, ↑ prolactin, ↑ response to nafarelin–a GnRH-gonadotropin-releasing hormone agonist that causes a ♂ pattern response, suggesting that PCO has defective regulation of 17-hydroxylase and C-17,20-lyase; sterility, menstrual abnormalities and hyperandrogenism ± associated with valproate therapy for epilepsy. See HAIR-AN syndrome.


containing many cysts.

polycystic kidney disease
see polycystic kidney disease.
polycystic liver
congenital anomaly in which cystic remnants of the bile duct occur in the liver; the bile duct is patent; seen in kittens, pups, piglets.
polycystic ovarian disease
multiple thin-walled cysts in one or both ovaries of the mature bitch; may cause hyperestrogenism.
polycystic pancreas
cystic pancreatic and bile ducts and polycystic kidneys may occur in the same patient.
polycystic renal disease
see polycystic kidney disease.
References in periodicals archive ?
Efficacy of combined metformin-letrozole in comparison with metformin-clomiphene citrate in clomiphene-resistant infertile women with polycystic ovarian disease.
Study of the mucus cycle has also led to improvement in the treatment of stress, and the correct use of progesterone treatment of pre-menstrual syndrome, postpartum depression, recurrent ovarian cysts, and polycystic ovarian disease.
Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease.

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